Blar i forfatter Artikler, rapporter og annet (kjemi) "Einrem, Rune F."

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    • Amphiphilic Rhenium-Oxo Corroles as a New Class of Sensitizers for Photodynamic Therapy 

      Einrem, Rune F.; Alemayehu, Abraham; Borisov, Sergey M.; Ghosh, Abhik; Gederaas, Odrun Arna (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-27)
      A set of rhenium(V)-oxo <i>meso</i>-triarylcorroles bearing ester and carboxylic acid functionalities were synthesized with a view to determining their potential for photodynamic therapy. Toward this end, we measured their near-IR phosphorescence and their ability to sensitize singlet oxygen formation. The two esters studied, Re<sup>V</sup>O 5,10,15-tris(<i>meta</i>-carbomethoxyphenyl)corrole and ...

    • Regioselective formylation of rhenium-oxo and gold corroles: Substituent effects on optical spectra and redox potentials 

      Einrem, Rune F.; Jonsson, Einar Torfi; Teat, Simon J.; Settineri, Nicholas S.; Alemayehu, Abraham B.; Ghosh, Abhik (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-28)
      Vilsmeier–Haack formylation of ReO and Au meso-triarylcorroles over 16–18 hours affords moderate to good yields (47–65%) of the ReO-3-formyl and Au-3,17-diformyl derivatives in a highly regioselective manner. Formylation was found to effect substantial upshifts for redox potentials (especially the reduction potentials) as well as significant to dramatic redshifts for both the Soret and Q bands.

    • Simple, Axial Ligand-Mediated Route to Water-Soluble Iridium Corroles 

      Thomassen, Ivar K.; Rasmussen, Daniel; Einrem, Rune F.; Ghosh, Abhik (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-15)
      The synthesis and purification of water-soluble porphyrin-type compounds for photodynamic therapy and other medical applications is often a tedious exercise. Here, we have investigated the simple stratagem of adding a water-soluble axial ligand to the standard protocol for iridium insertion into simple meso-triarylcorroles. Early results showed that six-coordinate Ir[TpXPC](dna)2 derivatives, in ...

    • Synthesis and molecular structure of perhalogenated rhenium-oxo corroles 

      Alemayehu, Abraham B.; Einrem, Rune F.; McCormick‑McPherson, Laura J.; Settineri, Nicholas S.; Ghosh, Abhik (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-12)
      As part of our efforts to develop rhenium-oxo corroles as photosensitizers for oxygen sensing and photodynamic therapy, we investigated the potential <i>β</i>-perhalogenation of five ReO <i>meso</i>-tris(<i>para</i>-X-phenyl)corroles, Re[T<i>p</i>XPC](O) (X = CF<sub>3</sub>, H, F, CH<sub>3</sub>, and OCH<sub>3</sub>), with elemental chlorine and bromine. With Cl<sub>2</sub>, <i>β</i>-octachlorinated ...