Blar i forfatter Artikler, rapporter og annet (kjemi) "Engqvist, Magnus"

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    • Antimicrobial activity of amphipathic α,α-disubstituted β-amino amide derivatives against ESBL–CARBA producing multi-resistant bacteria; effect of halogenation, lipophilicity and cationic character 

      Paulsen, Marianne Hagensen; Ausbacher, Dominik; Bayer, Annette; Engqvist, Magnus; Hansen, Terkel; Haug, Tor; Anderssen, Trude; Andersen, Jeanette Hammer; Sollid, Johanna U. Ericson; Strøm, Morten B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-06)
      The rapid emergence and spread of multi-resistant bacteria have created an urgent need for new antimicrobial agents. We report here a series of amphipathic α,α-disubstituted β-amino amide derivatives with activity against 30 multi-resistant clinical isolates of Gram-positive and Gram-negative bacteria, including isolates with extended spectrum β-lactamase – carbapenemase (ESBL-CARBA) production. A ...

    • Palladium(0)-Catalyzed Cross-Couplings of 2-Bromophosphinine 

      Kostenko, Nataliya; Eriksson, Cecilia; Engqvist, Magnus; Villa Gonzalez, Susana; Bayer, Annette (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-05-21)
      A new Negishi-type cross-coupling of 2-bromophosphinine has been developed. The new method expands the scope of palladium-catalyzed couplings to monobromophosphinines, which have been considered as poor substrates so far. Moreover, aryl-, alkenyl-, and alkynylzinc bromides were found to be effective coupling partners.