• Development of potent cholinesterase inhibitors based on a marine pharmacophore 

      Elumalai, Vijayaragavan; Trobec, Tomaz; Grundner, Maja; Labriere, Christophe; Frangez, Robert; Sepcic, Kristina; Hansen, Jørn H; Svensson, Johan (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-01)
      The management of neurological disorders such as dementia associated with Alzheimer's or Parkinson's disease includes the use of cholinesterase inhibitors. These compounds can slow down the progression of these diseases and can also be used in the treatment of glaucoma and myasthenia gravis. The majority of the cholinesterase inhibitors used in the clinic are derived from natural products and our ...