• Mobile group I introns at nuclear rDNA position L2066 harbor sense and antisense homing endonuclease genes intervened by spliceosomal introns 

      Lian, Kjersti; Furulund, Betty Martine Normann; Tveita, Anders Aune; Haugen, Peik; Johansen, Steinar Daae (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-08)
      Background: Mobile group I introns encode homing endonucleases that confer intron mobility initiated by a double-strand break in the intron-lacking allele at the site of insertion. Nuclear ribosomal DNA of some fungi and protists contain mobile group I introns harboring His-Cys homing endonuclease genes (HEGs). An intriguing question is how protein-coding genes embedded in nuclear ribosomal DNA ...
    • Structural Organization of S516 Group I Introns in Myxomycetes 

      Furulund, Betty Martine Normann; Karlsen, Bård Ove; Babiak, Igor; Haugen, Peik; Johansen, Steinar Daae (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-25)
      Group I introns are mobile genetic elements encoding self-splicing ribozymes. Group I introns in nuclear genes are restricted to ribosomal DNA of eukaryotic microorganisms. For example, the myxomycetes, which represent a distinct protist phylum with a unique life strategy, are rich in nucleolar group I introns. We analyzed and compared 75 group I introns at position 516 in the small subunit ...