Blar i forfatter Artikler, rapporter og annet (kjemi) "Mackenzie, Alasdair"

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    • Discovery and characterization of a thermostable two-domain GH6 endoglucanase from a compost metagenome 

      Jensen, Marianne Slang; Fredriksen, Lasse; Mackenzie, Alasdair; Pope, Phillip; Leiros, Ingar; Chylenski, Piotr; Williamson, Adele Kim; Christopeit, Tony; Østby, Heidi; Vaaje-Kolstad, Gustav; Eijsink, Vincent (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-24)
      Enzymatic depolymerization of recalcitrant polysaccharides plays a key role in accessing the renewable energy stored within lignocellulosic biomass, and natural biodiversities may be explored to discover microbial enzymes that have evolved to conquer this task in various environments. Here, a metagenome from a thermophilic microbial community was mined to yield a novel, thermostable cellulase, named ...

    • Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae 

      Mazurkewich, Scott; Helland, Ronny; Mackenzie, Alasdair; Eijsink, Vincent; Pope, Phillip Byron; Brändén, Gisela; Larsbrink, Johan (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-13)
      Chitin is one of the most abundant renewable organic materials found on earth. The chitin utilization locus in <i>Flavobacterium johnsoniae</i>, which encodes necessary proteins for complete enzymatic depolymerization of crystalline chitin, has recently been characterized but no detailed structural information on the enzymes was provided. Here we present protein structures of the <i>F. johnsoniae</i> ...