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Sequence analysis of nonulosonic acid biosynthetic gene clusters in Vibrionaceae and Moritella viscosa

Permanent link
https://hdl.handle.net/10037/19154
DOI
https://doi.org/10.1038/s41598-020-68492-3
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Date
2020-07-20
Type
Journal article
Tidsskriftartikkel
Peer reviewed

Author
Halsør, Marie-Josée Haglund; Altermark, Bjørn; Ræder, Inger Lin Uttakleiv
Abstract
Nonulosonic acid (NulO) biosynthesis in bacteria is directed by nab gene clusters that can lead to neuraminic, legionaminic or pseudaminic acids. Analysis of the gene content from a set mainly composed of Aliivibrio salmonicida and Moritella viscosa strains reveals the existence of several unique nab clusters, for which the NulO products were predicted. This prediction method can be used to guide tandem mass spectrometry studies in order to verify the products of previously undescribed nab clusters and identify new members of the NulOs family.
Publisher
Springer
Citation
Halsør, Altermark, Ræder. Sequence analysis of nonulosonic acid biosynthetic gene clusters in Vibrionaceae and Moritella viscosa. Scientific Reports. 2020;10(1)
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