In recent years antimicrobial peptides have gained a lot of attention due to their potential as a new generation of antibiotics combating the growing problem of antibiotic resistance. It is believed that the amphipathic structure of cationic peptides is a key feature for antimicrobial activity, and that this enables them to interact with the bacterial cell membrane. The conformational space of a ...

This thesis describes a new principle for the synthesis of thiophene from diketone. Thiophene is a five-membered heterocyclic aromatic compound containing one sulphur atom. The thiophene structure can be found in certain natural products and is also incorporated in several pharmacologically active compounds. The procedure described in the thesis uses the combination of graphite and metallic ...

The present work is on the total synthesis of a natural compound found in a mixture of secondary metabolite produced by an alga nearby the cost of Australia. The target molecule, the 4-bromo-3-butyl-5-(dibromomethylene)furan-2(5H)-one, has not previously been proposed. The synthetic route described in this thesis uses cheap and readily available starting materials and the target is reached after six ...

Mettede C-16 og C-18 klorerte fettsyrer ble syntetisert til bruk som miljøstandarder. De mettede klorerte fettsyrene hører sammen med en ny type miljøgift nemlig klorerte fettsyrer (ClFA). Dette er en type miljøgift som man per dags dato ikke har så mye kunnskap om, men som er blitt påvist i en rekke forskjellige fiskearter. Hvilken effekt de vil ha på mennesker eller andre pattedyr på toppen av ...