dc.contributor.author | Pandey, Sunil Kumar | |
dc.contributor.author | Guttormsen, Yngve | |
dc.contributor.author | Haug, Bengt Erik | |
dc.contributor.author | Hedberg, Christian | |
dc.contributor.author | Bayer, Annette | |
dc.date.accessioned | 2015-01-02T07:30:41Z | |
dc.date.available | 2015-12-16T06:50:04Z | |
dc.date.issued | 2014 | |
dc.description.abstract | The first total synthesis of breitfussin A and B is described. The approach features two palladium-catalyzed cross-couplings installing the indole and pyrrole onto the oxazole core and selective lithiation/iodination of a common indole–oxazole fragment providing 2,4-diiodinated or 2-iodinated oxazoles as potential precursors for breitfussin A and B, respectively. An unexpected acid promoted deiodination was utilized in the synthesis of breitfussin B. Comparison of the synthetic material with previously reported spectral data of isolated breitfussin A and B verified the structure of the breitfussin framework. | |
dc.identifier.citation | Organic Letters, 2015, 17 (1), pp 122–125. | en |
dc.identifier.cristinID | FRIDAID 1184158 | |
dc.identifier.doi | 10.1021/ol503348n | |
dc.identifier.issn | 1523-7060 | |
dc.identifier.uri | https://hdl.handle.net/10037/6971 | |
dc.identifier.urn | URN:NBN:no-uit_munin_6571 | |
dc.language.iso | eng | en |
dc.publisher | American Chemical Society | en |
dc.rights.accessRights | openAccess | |
dc.subject | VDP::Matematikk og Naturvitenskap: 400::Kjemi: 440::Organisk kjemi: 441 | en |
dc.subject | VDP::Mathematics and natural science: 400::Chemistry: 440::Organic chemistry: 441 | en |
dc.title | A Concise Total Synthesis of Breitfussin A and B | en |
dc.type.version | acceptedVersion | |
dc.type | Journal article | en |
dc.type | Tidsskriftartikkel | en |
dc.type | Peer reviewed | en |