Blar i forfatter "Eriksen, Bjørn Odvar"

Viser treff 41-51 av 51

    • Renal Functional Response-Association With Birth Weight and Kidney Volume 

      Lillås, Bjørn Steinar Demma; Tøndel, Camilla; Melsom, Toralf; Eriksen, Bjørn Odvar; Marti, Hans Peter; Vikse, Bjørn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-20)
      <b><p>Introduction:</b> Renal functional response (RFR) is the acute increase in glomerular filtration rate (GFR) after a protein load. Low RFR is a marker of single nephron hyperfiltration. Low birth weight (LBW) is associated with reduced number of nephrons, lower kidney function, and smaller kidneys in adults. In the present study, we investigate the associations among LBW, kidney volume, and ...

    • Serum Matrix Metalloproteinase 7 and accelerated glomerular filtration rate decline in a general non-diabetic population 

      Enoksen, Inger Therese T.; Svistounov, Dmitri; Norvik, Jon Viljar; Stefansson, Vidar Tor Nyborg; Solbu, Marit Dahl; Eriksen, Bjørn Odvar; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
      Background. Age-related reduction of glomerular filtration rate (GFR) is a major contributor to the global chronic kidney disease (CKD) epidemic. We investigated whether baseline serum levels of the pro-fibrotic matrix metalloproteinase 2 (MMP2), MMP7 and their inhibitor, tissue inhibitor of metalloproteinase 1 (TIMP1), which mediates fibrosis development in aging animals, were associated with ...

    • Sex Differences in Age-Related Loss of Kidney Function 

      Melsom, Toralf; Norvik, Jon Viljar; Enoksen, Inger Therese; Stefansson, Vidar Tor Nyborg; Mathisen, Ulla Dorte; Fuskevåg, Ole Martin; Jenssen, Trond Geir; Solbu, Marit Dahl; Eriksen, Bjørn Odvar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-30)
      Background - CKD is more prevalent in women, but more men receive kidney replacement therapy for kidney failure. This apparent contradiction is not well understood.<p> <p>Methods - We investigated sex differences in the loss of kidney function and whether any sex disparities could be explained by comorbidity or CKD risk factors. In the Renal Iohexol Clearance Survey (RENIS) in northern Europe, ...

    • Supplemented ERA-EDTA Registry data evaluated the frequency of dialysis, kidney transplantation, and comprehensive conservative management for patients with kidney failure in Europe 

      Stel, Vianda S.; de Jong, Rianne; Kramer, Anneke; Andrusev, Anton M.; Baltar, José M.; Barbullushi, Myftar; Bell, Samira; De La Nuez, Pablo Castro; Cernevskis, Harijs; Couchoud, Cécile; de Meester, Johan; Eriksen, Bjørn Odvar; Garneata, Lilliana; Golan, Eliezer; Helve, Jaakko; Hemmelder, Marc; Hommel, Kristine; Ioannou, Kyriakos; Jarraya, Faiçal; Kantaria, Nino; Kerschbaum, Julia; Komissarov, Kirill S.; Magaz, Ángela; Mercadal, Lucile; Ots-Rosenberg, Mai; Palsson, Runolfur; Rahmel, Axel; Rydell, Helena; Savino, Manuela; Seyahi, Nurhan; Roblero, María Fernanda Slon; Stojceva-Taneva, Olivera; Schaft, Arjan van der; Vazelov, Evgueniy S.; Ziginskiene, Edita; Zurriaga, Oscar; Vanholder, Raymond C.; Massy, Ziad A.; Jager, Kitty J (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-07)
      The aims of this study were to determine the frequency of dialysis and kidney transplantation and to estimate the regularity of comprehensive conservative management (CCM) for patients with kidney failure in Europe. This study uses data from the ERA-EDTA Registry. Additionally, our study included supplemental data from Armenia, Germany, Hungary, Ireland, Kosovo, Luxembourg, Malta, Moldova, ...

    • Uric acid is a risk factor for ischemic stroke and all-cause mortality in the general population: a gender specific analysis from The Tromsø Study 

      Storhaug, Hilde-Merete; Norvik, Jon Viljar; Toft, Ingrid; Eriksen, Bjørn Odvar; Løchen, Maja-Lisa; Zykova, Svetlana; Solbu, Marit Dahl; White, Sarah; Chadban, S; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: The role of serum uric acid as an independent predictor of cardiovascular disease and death is uncertain in the general population. Adjustments for additional cardiovascular risk factors have not been consistent. We examined the association of serum uric acid with all-cause mortality, ischemic stroke and myocardial infarction in a prospective population based study, with several traditional ...

    • Uric acid is associated with microalbuminuria and decreased glomerular filtration rate in the general population during 7 and 13 years of follow-up: The Tromsø Study 

      Storhaug, Hilde-Merete; Toft, Ingrid; Norvik, Jon Viljar; Jenssen, Trond Geir; Eriksen, Bjørn Odvar; Melsom, Toralf; Løchen, Maja-Lisa; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-11)
      Background: The role of uric acid in development of renal dysfunction (RD) remains controversial. Earlier studies have reported inconsistent results, possibly because of their varying ability to adjust for confounding. The impact of longitudinal change in uric acid on renal outcome has not been assessed previously. We aimed to study the impact of change in serum uric acid (SUA) as well as baseline ...

    • Uric acid predicts mortality and ischaemic stroke in subjects with diastolic dysfunction: the Tromsø Study 1994-2013 

      Norvik, Jon Viljar; Schirmer, Henrik; Ytrehus, Kirsti; Storhaug, Hilde-Merete; Jenssen, Trond Geir; Eriksen, Bjørn Odvar; Mathiesen, Ellisiv B.; Løchen, Maja-Lisa; Wilsgaard, Tom; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01-31)
      Aims: To investigate whether serum uric acid predicts adverse outcomes in persons with indices of diastolic dysfunction in a general population. <br>Methods and results: We performed a prospective cohort study among 1460 women and 1480 men from 1994 to 2013. End- points were all-cause mortality, incident myocardial infarction, and incident ischaemic stroke. We strati fi ed the analyses ...

    • Urinary excretion of epidermal growth factor and rapid loss of kidney function 

      Norvik, Jon Viljar; Harskamp, Laura R.; Nair, Viji; Shedden, Kerby; Solbu, Marit Dahl; Eriksen, Bjørn Odvar; Kretzler, Matthias; Gansevoort, Ron T.; Ju, Wenjun; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-17)
      Background - Lower urinary excretion of the kidney tubule–specific biomarker epidermal growth factor (uEGF) is associated with increased risk of renal function [glomerular filtration rate (GFR)] loss in diabetes and in patients with established chronic kidney disease (CKD). We investigated whether uEGF is associated with rapid GFR decline or incident CKD in the general population.<p> <p>Methods ...

    • Urinary Markers of Oxidative Stress Are Associated With Albuminuria But Not GFR Decline 

      Schei, Jørgen; Fuskevåg, Ole-Martin; Stefansson, Vidar Tor Nyborg; Solbu, Marit Dahl; Jenssen, Trond Geir; Eriksen, Bjørn Odvar; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-07)
      <p><i>Introduction</i>: Markers of oxidative stress increase with age and are prevalent with chronic kidney disease. However, the role of oxidative stress markers as predictors for kidney function decline in the general population is unclear.</p> <p><i>Methods</i>: We investigated whether a baseline urinary excretion of oxidative DNA damage (8-oxo-7,8-dihydro-2′-deoxyguanosine [8-oxodG]) and ...

    • Urinary orosomucoid is associated with diastolic dysfunction and carotid arteriopathy in the general population. Cross-sectional data from the Tromsø study 

      Andreassen, Runa Marie; Kronborg, Jens; Schirmer, Henrik; Mathiesen, Ellisiv B.; Melsom, Toralf; Eriksen, Bjørn Odvar; Jenssen, Trond Geir; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-02)
      Objectives. Urinary albumin excretion is a risk marker for cardiovascular disease (CVD). Studies suggest that urinary orosomucoid may be a more sensitive marker of general endothelial dysfunction than albuminuria. The aim of this population-based cross-sectional study was to examine the associations between urinary orosomucoid to creatinine ratio (UOCR), urinary albumin to creatinine ratio ...

    • Validation of eGFR for Detecting Associations Between Serum Protein Biomarkers and Subsequent GFR Decline 

      Enoksen, Inger Therese Tønsberg; Rinde, Nikoline Balteskard; Svistounov, Dmitri; Norvik, Jon Viljar Porserud; Solbu, Marit Dahl; Eriksen, Bjørn Odvar; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08)
      Significance Statement - eGFR from creatinine, cystatin C, or both has been primarily used in search of biomarkers for GFR decline. Whether the relationships between biomarkers and eGFR decline are similar to associations with measured GFR (mGFR) decline has not been investigated. This study revealed that some biomarkers showed statistically significant different associations with eGFR decline ...