Purc, Anna; Koszarna, Beata; Iachina, Irina; Friese, Daniel Henrik; Tasior, Mariusz; Sobczyk, Krzysztof; Pedzinski, Tomasz; Brewer, Jonathan; Gryko, Daniel T (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-07)
An in-depth investigation of the reaction of substituted salicylaldehydes with chloroacetonitrile led to the
development of new conditions for the synthesis of 2-cyanobenzofurans. The crucial improvement lies in
the use of phase-transfer catalysis in the second step, i.e., intramolecular aldol type condensation. In a
two-step process, the reactants were transformed into a library of 3,6-bis(ben ...