• Hypothalamic tanycytes as mediators of maternally programmed seasonal plasticity 

      Melum, Vebjørn Jacobsen; Sáenz de Miera, Cristina; Markussen, Fredrik Andreas Fasth; Cazarez Marquez, Fernando; Jaeger, Catherine; Sandve, Simen Rød; Simonneaux, Valérie; Hazlerigg, David Grey; Wood, Shona Hiedi (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-12)
      In mammals, maternal photoperiodic programming (MPP) provides a means whereby juvenile development can be matched to forthcoming seasonal environmental conditions.<sup>1–4</sup> This phenomenon is driven by in utero effects of maternal melatonin<sup>5–7</sup> on the production of thyrotropin (TSH) in the fetal pars tuberalis (PT) and consequent TSH receptor-mediated effects on tanycytes lining ...
    • An integrative view of mammalian seasonal neuroendocrinology 

      Dardente, Hugues; Wood, Shona Hiedi; Ebling, Francis; Sáenz de Miera, Cristina (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-06)
      Seasonal neuroendocrine cycles that govern annual changes in reproductive activity, energy metabolism and hair growth are almost ubiquitous in mammals that have evolved at temperate and polar latitudes. Changes in nocturnal melatonin secretion regulating gene expression in the pars tuberalis (PT) of the pituitary stalk are a critical common feature in seasonal mammals. The PT sends signal(s) to the ...