Blar i forfatter "Subbotina, Anna"
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Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhibit cellular cGMP efflux
Subbotina, Anna; Ravna, Aina Westrheim; Lyså, Roy Andre; Abagyan, Ruben; Bugno, Ryszard; Sager, Georg (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-17)<p><i>Objectives</i>: To determine the ability of 11 sildenafil analogues to discriminate between cyclic nucleotide phosphodiesterases (cnPDEs) and to characterise their inhibitory potencies (<kursiv>K</kursiv><sub>i</sub> values) of PDE5A1‐dependent guanosine cyclic monophosphate (cGMP) hydrolysis.</p> <p><i>Methods</i>: Sildenafil analogues were identified by virtual ligand screening (VLS) ... -
Quality of life following renal sympathetic denervation in treatment-resistant hypertensive patients: a two-year follow-up study
Hanssen, Tove Aminda; Subbotina, Anna; Miroslawska, Atena; Solbu, Marit Dahl; Steigen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-10)Objective. Hypertension is a significant health burden. In the last 10 years, renal sympathetic denervation has been tested as a potential treatment option for a select group of patients with treatmentresistant hypertension. The aim of this study was to broadly assess the quality of life in patients undergoing renal sympathetic denervation with two years’ follow-up. Materials and methods. Patients ...