Crowe-McAuliffe, Caillan; Murina, Victoriia; Turnbull, Kathryn Jane; Huch, Susanne; Kasari, Marje; Takada, Hiraku; Nersisyan, Lilit; Sundsfjord, Arnfinn; Hegstad, Kristin; Atkinson, Gemma C.; Pelechano, Vicent; Wilson, Daniel N.; Hauryliuk, Vasili (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-06)
PoxtA and OptrA are ATP binding cassette (ABC) proteins of the F subtype (ABCF). They
confer resistance to oxazolidinone and phenicol antibiotics, such as linezolid and chloramphenicol, which stall translating ribosomes when certain amino acids are present at a
defined position in the nascent polypeptide chain. These proteins are often encoded on
mobile genetic elements, facilitating their rapid ...