Background<p> <p>Effect-size underestimation impedes biomarker identification. Long follow-up time in prospective studies attenuates effect-size estimates for transient biomarkers, while disease category–specific biomarkers are affected by merging of categories. Venous thromboembolism (VTE) encompasses deep vein thrombosis (DVT) and pulmonary embolism (PE). <p>Objectives <p>(i) To re-analyze untargeted ...

Background: The Strengths and Difficulties Questionnaire (SDQ) is a frequently used behavioral screening instrument. However, its psychometric properties have been rarely examined among children with intellectual and developmental disabilities (IDD).<p> <p>Aims: The main aims of this study were to examine the internal consistency (i.e., McDonald’s Omega), the convergent validity (by correlating ...

The effects of early thermal environment on growth, age at maturity, and sexual size dimorphism in Arctic charr (Salvelinus alpinus) are investigated. This study is a 654-day long rearing trial split into two sequential experimental phases termed EP1 and EP2 and lasting 315 and 339 days, respectively. EP1 started at the end of the yolk sac stage when the experimental fish were divided into three ...

Increasing exploration and exploitation activity in the Arctic Ocean has intensified maritime traffic in the Barents Sea. Due to the sparse population and insufficient oil spill response infrastructure on the extensive Barents Sea shoreline, it is necessary to address the possibility of offshore accidents and study hazards to the local environment and its resources. Simulations of surface oil ...

The importance of cold-water blue carbon as biological carbon pumps that sequester carbon into ocean sediments is now being realised. Most polar blue carbon research to date has focussed on deep water, yet the highest productivity is in the shallows. This study measured the functional biodiversity and carbon standing stock accumulated by shallow-water (<25 m) benthic assemblages on both hard and ...

Introduction: Identification of individuals at high risk of developing type 2 diabetes mellitus (T2DM) is important for early prevention of the disease. Once T2DM is established, it is difficult to treat and is associated with cardiovascular complications and increased mortality. We aimed to describe pre- and post-diagnostic changes in blood biomarker concentrations over 30 years in individuals ...

<p><b>Introduction:</b> Rewarming from accidental hypothermia is often complicated by hypothermia-induced cardiovascular dysfunction, which could lead to shock. Current guidelines do not recommend any pharmacological treatment at core temperatures below 30°C, due to lack of knowledge. However, previous in vivo studies have shown promising results when using phosphodiesterase 3 (PDE3) inhibitors, ...

Meltwater drainage across the surface of the Greenland ice sheet (GrIS) is well constrained by measurements and modeling, yet despite its critical role, knowledge of its transit through the subglacial environment remains limited. Here we present a subglacial hydrological analysis of a land-terminating sector of the GrIS at unprecedented resolution that predicts the routing of surface-derived meltwater ...

Institutt for samfunnsmedisin ved Universitetet i Tromsø har siden slutten av 1980-tallet hatt samarbeide med klinikere og forskere fra Universitetet i Arkhangelsk. Dette samarbeidet har resultert i utveksling av helsepersonell og studenter, flere utviklings- og forskningsprosjekter har blitt igangsatt og avsluttet, og en rekke felles møter og konferanser om situasjonen for folkehelsen i Russland ...

A large-scale multidisciplinary mesocosm experiment in an Arctic fjord (Kongsfjorden, Svalbard; 78°56.2′N) was used to study Arctic marine food webs and biogeochemical elements cycling at natural and elevated future carbon dioxide (CO2) levels. At the start of the experiment, marine-derived chromophoric dissolved organic matter (CDOM) dominated the CDOM pool. Thus, this experiment constituted a ...