Bakgrunn Kateterablasjon er en veletablert behandlingsmetode for pasienter med symptomatisk atrieflimmer, og har vært utført ved Universitetssykehuset Nord-Norge siden 2009. Formålet med studien var å evaluere behandlingsresultatene etter kateterbasert ablasjonsbehandling av atrieflimmer ved UNN Tromsø fra 2013 til og med 2019. Materiale og metode Retrospektiv kohortstudie basert på 574 ...

Background: As transcatheter aortic valve implantation (TAVI) has expanded the treatment options to otherwise inoperable patients, it has become as prevalent as surgical aortic valve replacement. TAVI infective endocarditis (IE) has thereby become a feared complication. IE is heterogenous in its presentation, identifying characteristics and diagnostic criteria among these patients is crucial in ...

En undersøkelse av om dagens eiendomsskatteregler kan brukes til å trekke inn grunnrenten som finnes i oppdrettsnæringen.

This thesis historically examines the disease known as tuberculosis in Tromsø town from 1878 to 1920. It explores the effects of gendered, societal, and economic differences upon tuberculosis mortality. It primarily uses quantitative sources, in the form of local burial registers, cadastral registers, annual medical reports and population censuses. The thesis has found that tuberculosis mortality ...

Staphylococcus aureus (S. aureus) needs iron to survive and replicate and has evolved systems to harvest iron from its host. In humans, excess iron could potentially increase the risk of S. aureus carriage and infections. Moreover, iron plays a vital role in the development and function of the host immune system. Adolescence is a growth spurt period with increased iron requirements. The aim of this ...

The rise in frequency of antibiotic resistant pathogenic bacteria makes the need for new treatment options for previously curable bacterial infections ever more important. In the process of discovering and developing antibacterial agents, one powerful approach has been borrowing wisdom from nature. Antimicrobial peptides (AMPs) are critical components of the innate immune systems found in almost all ...

Exocytosis is a fundamental process in physiology, that ensures communication between cells, organs and even organisms. Hormones, neuropeptides and antibodies, among other cargoes are packed in exocytic vesicles that need to reach and fuse with the plasma membrane to release their content to the extracellular milieu. Hundreds of proteins participate in this process and several others in its regulation. ...

Nanomedicine has been, to a certain degree, a success story in the development of superior anticancer therapies. However, there are tumors that remain a huge challenge for nanoformulations, for instance, brain tumors such as glioblastoma, the most common and aggressive brain tumor. To utilize the fact that such tumors are characterized by an acidic extracellular environment, we selected pH-responsive ...

Surgical aortic valve replacement (SAVR) has until the last decade been the standard treatment for patients with aortic stenosis (AS). However, many patients were not offered surgical treatment due to high age or unacceptable surgical risk estimated by surgical risk scores. Transcatheter aortic valve implantation (TAVI) is a less invasive treatment modality where the valve is implanted using a ...

The small-aperture Spitsbergen seismic array (SPITS) has been in continuous operation at Janssonhaugen for decades. The high-Arctic location in the Svalbard archipelago makes SPITS an ideal laboratory for the study of cryoseisms, a nontectonic class of seismic events caused by freeze processes in ice, ice–soil, and ice–rock materials. We extracted a catalog of > 100 000 events from the nearly ...