<p>Natural products have been used by humans since ancient times as benefactors for improved health. Prior to modern medicine and chemistry, these compounds remained hidden in the plants, animals and other organisms used to heal inflammation, wounds, headache and stomachache among other conditions. Since the start of modern drug discovery with isolation of morphine in 1805, numerous natural products ...

Chronic pain is a major health challenge, and musculoskeletal pain is among the main contributors to years lived with disability worldwide. Earlier research found an association between cold exposure at work and musculoskeletal pain. However, the literature is scarce, especially regarding chronic pain. It is a common belief that weather affects pain experience, but the literature on this topic is ...

Owing to increased access to the Internet and the development of electronic commerce, e-commerce has become a common method of shopping in all countries. The purpose of this study is more precisely to research e-commerce diversity in Europe at the regional level and develop the conception of “E-commerce Supply Chain Management”. Statistical data derived from the European Statistical Ofce were applied ...

The biodynamics and biokinetics of sex hormones are complex. In addition to the classical steroid receptors (nuclear receptors), these hormones act through several non-genomic mechanisms. Modulation of ABC-transporters by progesterone represents a non-genomic mechanism. In the present study, we employed inside out vesicles from human erythrocytes to characterize high affinity cGMP transport by ABCC5 ...

This study explores the influence of geographical location on young pupils’ educational orientations and their transition from lower to upper secondary school; it pays particular attention to the voices of male youths from a rural area. More specifically, it investigates the interplay between gender and geographical contexts and the significance of these factors in understanding the processes ...

Mitochondria are essential energy-providing organelles of particular importance in energy-demanding tissue such as the heart. The production of mitochondria-derived vesicles (MDVs) is a cellular mechanism by which cells ensure a healthy pool of mitochondria. These vesicles are small and fast-moving objects not easily captured by imaging. In this work, we have tested the ability of the optical ...

The changing Arctic environment is affecting zooplankton that support its abundant wildlife. We examined how these changes are influencing a key zooplankton species, Calanus finmarchicus, principally found in the North Atlantic but expatriated to the Arctic. Close to the ice-edge in the Fram Strait, we identified areas that, since the 1980s, are increasingly favourable to C. finmarchicus. Field-sampling ...

Sammendrag I forbindelse med Lurøy kommunes sterke fokus på enøk ønsker de å se hvilken nytte ulike tiltak kan ha på eksisterende bygg. Størsteparten av bygningsmassen til Lurøy kommune er fra 1960- til 1980-tallet. Flere av FNs bærekraftsmål er aktuell for oppgaven. Strøm, fremtidig utsikt for energipris, miljø, resirkulering, gjenbruk og oppgradering av eksisterende boliger og begrense sløsing ...

The e-commerce industry is experiencing rapid growth, and growing customer expectations and demand challenges the industry to find more cost-efficient ways of performing the last-mile deliveries. Drones have in recent years been a hot topic, and with high versatility and several application areas it may be the answer to the challenge. In this project a Vans-and-Drones System for Last-Mile Delivery ...

This report discusses the possibility for wireless charging solutions for electric vessels, with a focus on offshore wind turbine service. Where the charging time is minimal and safety for crew is important. Different types of wireless technologies have been studied, where the Inductive power transfer (IPT) is shown to be the preferred technology. Inductive power transfer (IPT) grants a safe ...