Viser treff 20381-20400 av 37151

    • Correlation between baseline GFR and subsequent change in GFR in Norwegian adults without diabetes and in Pima Indians 

      Melsom, Toralf; Nair, Viji; Schei, Jørgen; Mariani, Laura; Stefansson, Vidar Tor Nyborg; Harder, Jennifer L.; Jenssen, Trond Geir; Solbu, Marit Dahl; Norvik, Jon Viljar; Looker, Helen; Knowler, William C.; Kretzler, Matthias; Nelson, Robert G.; Eriksen, Bjørn Odvar (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-28)
      <p><i>Rationale & Objective - </i>An elevated glomerular filtration rate (GFR), or renal hyperfiltration, may predispose individuals to subsequent rapid GFR decline in diabetes, obesity, and metabolic syndrome. Although this hypothesis is supported by results of experimental studies, the importance of hyperfiltration at the population level remains controversial. We investigated whether higher ...
    • Kan forankringseffekten brytes? En tilnærming mot underbevisste prosesser 

      Larsen, Karoline Gjertsen (Master thesis; Mastergradsoppgave, 2019-05-02)
      Hensikten med studien var å undersøke om forankringseffekten kunne elimineres, og om dette kunne gjennomføres ved en enkel og lite krevende metode. Forankringseffekten er kjent for sin robuste karakteristikk og tidligere studier har som regel feilet i å redusere eller eliminere effekten. Studien er utviklet på bakgrunn av Selective Availability-modellen (Strack, Mussweiler & Kruglanski, 1997) som ...
    • Nevrotisisme og Ansiktspersepsjon: En Kvantitativ Studie av Sammenhengen mellom Persepsjon av Ansiktsuttrykk og Grad av Nevrotisisme 

      Nordling, Thyra Sæther; Skaue, Carmen Wilsgård (Master thesis; Mastergradsoppgave, 2019-05-02)
      The purpose of this study was to examine the relationship between facial emotion perception (bias and sensitivity) and degree of neuroticism. A limited amount of studies have been conducted in this area. Neuroticism is a possible risk factor for developing certain mental disorders (i.e. anxiety and depression). Studies conducted on clinical samples often report negative biases in the identification ...
    • Individuelle forskjeller med betydning for spatiale ferdigheter og perspektivtaking 

      Stensland-Bugge, Thea; Wiik, Ida Karine Larsen (Master thesis; Mastergradsoppgave, 2019-05-01)
      Forskning innen spatial kognisjon skiller tradisjonelt mellom objektbaserte og miljøbaserte spatiale evner. I vår studie ønsket vi å undersøke kjønnsforskjeller i objektbaserte spatiale evner målt med Mental Rotation Task (MRT), og hvordan kjønnsforskjellen påvirkes av spatial angst og personlighetstrekket emosjonell stabilitet. Vi ville også utforske i hvilken grad venstre/høyre diskriminering, ...
    • Kan high definition transcranial direct current stimulation (HD-tDCS) over dorsolateral prefrontal korteks (DLPFK) forbedre hukommelses- og/eller oppmerksomhetsfunksjon ved mild Alzheimers sykdom? 

      Jørvum, Grethe; Trøite Johnsen, Ingvild (Master thesis; Mastergradsoppgave, 2019-04-29)
      Alzheimers Sykdom (AS) er den vanligste demensformen, og forekomsten øker. Behovet for effektiv behandling er stort, men manglende. Flere studier fremmer High Definition Transcranial Direct Current Stimulation (HD-tDCS) som behandlingsmetode. Denne studien undersøkte om HD-tDCS over venstre dorsolateral prefrontal korteks (vDLPFK) medførte forbedring i hukommelses- og/eller oppmerksomhetsfunksjon ...
    • Complexity revealed in the greening of the Arctic 

      Myers-Smith, Isla H.; Kerby, Jeffrey T.; Phoenix, Gareth K.; Bjerke, Jarle W.; Epstein, Howard E.; Assmann, Jakob J.; John, Christian; Andreu-Hayles, Laia; Angers-Blondin, Sandra; Beck, Pieter S. A.; Berner, Logan T.; Bhatt, Uma S.; Bjorkman, Anne D.; Blok, Daan; Bryn, Anders; Christiansen, Casper Tai; Cornelissen, J. Hans C.; Cunliffe, Andrew M.; Elmendorf, Sarah C.; Forbes, Bruce C.; Goetz, Scott J.; Hollister, Robert D.; de Jong, Rogier; Loranty, Michael M.; Macias-Fauria, Marc; Maseyk, Kadmiel; Normand, Signe; Olofsson, Johan; Parker, Thomas C.; Parmentier, Frans-Jan W.; Post, Eric; Schaepman-Strub, Gabriela; Stordal, Frode; Sullivan, Patrick F.; Thomas, Haydn J.D.; Tømmervik, Hans; Treharne, Rachael; Tweedie, Craig E.; Walker, Donald A.; Wilmking, Martin; Wipf, Sonja (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-31)
      As the Arctic warms, vegetation is responding, and satellite measures indicate widespread greening at high latitudes. This ‘greening of the Arctic’ is among the world’s most important large-scale ecological responses to global climate change. However, a consensus is emerging that the underlying causes and future dynamics of so-called Arctic greening and browning trends are more complex, variable ...
    • Steps to unlocking ecosystem based fisheries management: Towards displaying the N dimensional potato 

      Pope, John; Hegland, Troels Jacob; Ballesteros, Marta; Nielsen, Kåre Nolde; Mika, Rahikainen (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-28)
      Any ecosystem based fisheries management system is necessarily faced with the problem of multiple objectives that trade-off against one another. Typically, objectives such as the maximization of yield, employment or profit or minimizing environmental impacts will be optimized in different parts of the decision space, which is formed of the fishing mortality rates that can be applied to the various ...
    • Targeting AXL and the DNA damage response pathway as a novel therapeutic strategy in melanoma 

      Karlsen, Karine Flem; McFadden, Erin; Omar, Nasrin; Haugen, Mads Haugland; Øy, Geir Frode; Ryder, Truls; Gullestad, Hans Petter; Hermann, Robert; Mælandsmo, Gunhild Mari; Flørenes, Vivi Ann (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-23)
      Receptor tyrosine kinase AXL is found upregulated in various types of cancer, including melanoma, and correlates with an aggressive cancer phenotype, inducing cell proliferation and epithelial-to-mesenchymal transition. Additionally, AXL has recently been linked to chemotherapy resistance and inhibition of AXL is found to increase DNA damage and reduce expression of DNA repair proteins. In light of ...
    • Seasonal dynamics of a permafrost landscape, Adventdalen, Svalbard, investigated by InSAR 

      Rouyet, Line; Lauknes, Tom Rune; Christiansen, Hanne H; Strand, Sarah Marie; Larsen, Yngvar (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-19)
      Nordenskiöld Land in Central Spitsbergen, Svalbard is characterized as a high latitude, high relief periglacial landscape with permafrost occurring both in mountains and lowlands. Freezing and thawing of the active layer causes seasonal frost heave and thaw subsidence, while permafrost-related mass-wasting processes induce downslope ground displacements on valley sides. Displacement rate varies ...
    • The First International Conference on 'Processes and Palaeo-Environmental Changes in the Arctic: From Past to Present' (PalaeoArc) 

      Lyså, Astrid; Benediktsson, Ívar Örn; Emery, Andy; Gregoire, Lauren; Jennings, Anne; Morigi, Caterina; Müller, Juliane; O'Regan, Matt; Sarala, Pertti; Stokes, Chris; Szczuciński, Witold; Winsborrow, Monica (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-13)
      The new international network PalaeoArc (Processes and Palaeo Environmental Changes in the Arctic: From Past to Present) held its first meeting in Poznan, 20-24 May 2019. The meeting was hosted by the Faculty of Geographical and Geological Sciences, Adam Mickiewicz University, Poznan, and organized by a local committee chaired by Witold Szczuciński.
    • Phthalate metabolites in harbor porpoises (Phocoena phocoena) from Norwegian coastal waters 

      Rian, May Britt; Vike-Jonas, Kristine; Gonzalez, Susana Villa; Ciesielski, Tomasz Maciej; Venkatraman, Vishwesh; Lindstrøm, Ulf; Jenssen, Bjørn Munro; Asimakopoulos, Alexandros (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-03)
      The exposure of marine mammals to phthalates has received considerable attention due to the ubiquitous occurrence of these pollutants in the marine environment and their potential adverse health effects. The occurrence of phthalate metabolites is well established in human populations, but data is scarce for marine mammals. In this study, concentrations of 17 phthalate metabolites were determined in ...
    • From policy to practice: Implementation of changes in law to support and protect children of ill parents 

      Skogøy, Bjørg Eva (Doctoral thesis; Doktorgradsavhandling, 2019-11-22)
      <p>Children of parents with serious forms of illness have shown to be vulnerable to developing a wide variety of psychosocial problems themselves. The research literature strongly indicates that preventive interventions may protect against well-documented transgenerational risk factors and strengthen the children’s resilience by promoting protective factors. Despite this knowledge, there is a gap ...
    • Prediction of Neighbor-dependent Microbial Interactions from Limited Population Data 

      Lee, Joon-Yong; Haruta, Shin; Kato, Souichiro; Bernstein, Hans Christopher; Lindemann, Stephen R.; Lee, Dong-Yup; Fredrickson, Jim K.; Song, Hyun-Seob (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-21)
      Modulation of interspecies interactions by the presence of neighbor species is a key ecological factor that governs dynamics and function of microbial communities, yet the development of theoretical frameworks explicit for understanding context-dependent interactions are still nascent. In a recent study, we proposed a novel rule-based inference method termed the Minimal Interspecies Interaction ...
    • Early markers of metabolic disease in obesity - A study of postprandial triglycerides, leptin and adiponectin interactions in the view of normal and dysregulated metabolism 

      Larsen, Maria Arlén (Doctoral thesis; Doktorgradsavhandling, 2019-12-06)
      Individuals in industrialized countries spend a substantial part of life in the non-fasting, postprandial state, which is also associated with increased oxidation and inflammation. Furthermore, a high body mass index (BMI) is the third cause of mortality in the world. In this PhD thesis, obese (BMI>30) individuals with and without metabolic disease (n=50) was included, in addition to a normal ...
    • Faglig program 2020 - 2025. Arkeologiske undersøkelser. Norges arktiske universitetsmuseum 

      Henriksen, Jørn Erik (Research report; Forskningsrapport, 2020)
      Dette er det andre Faglige programmet utarbeidet av Norges arktiske universitetsmuseum. Et av de viktigste formålene med programmet er å oppsummere kunnskapsstatus for derigjennom å identifisere kunnskapshull. Dette er avgjørende for å kunne skape et grunnlag for å kunne gjøre prioriteringer og å utforme faglige strategier for forvaltningsarkeologien. Dette programmet skiller seg nokså mye fra det ...
    • Performance of data enhancements and training optimization for neural network: A polyp detection case study 

      Henriksen, Fredrik Lund; Jensen, Rune; Stensland, Håkon Kvale; Johansen, Dag; Riegler, Michael; Halvorsen, Pål (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-05)
      Deep learning using neural networks is becoming more and more popular. It is frequently used in areas like video analysis, image retrieval, traffic forecast and speech recognition. In this respect, the learning and training process usually requires a lot of data. However, in many areas, data is scarce which is definitely the case in our medical application scenario, i.e., polyp detection in the ...
    • Grading of oral squamous cell carcinomas – Intra and interrater agreeability: Simpler is better? 

      Steigen, Sonja E; Søland, Tine Merete; Nginamau, Elisabeth Sivy; Laurvik, Helene; Costea, Daniela-Elena; Johannessen, Anne Christine; Jebsen, Peter Wilhelm; Bjerkli, Inger-Heidi; Uhlin-Hansen, Lars; Hadler-Olsen, Elin Synnøve (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-03)
      <i>Background</i> - Numerous studies have been presented on histological grading of oral squamous cell carcinomas (OSCC) for predicting survival, but uncertainty of their usefulness rises due to discordances of results. A scoring system should be robust and well validated, and intra‐ and interrater agreement can be used as a tool to visualize the strength of reproducibility.<p><p> <i>Methods</i> ...
    • The self-management work of food hypersensitivity. A study using a population-based cross-sectional study design and qualitative interviews 

      Jakobsen, Monika Dybdahl (Doctoral thesis; Doktorgradsavhandling, 2020-01-16)
      Food hypersensitivity (FH) has received increased attention in recent years; however, little attention has been given to the self-management work of FH. The aim of the present thesis was to explore the characteristics of women with FH, the nature of the self-management work of FH, and what makes women with FH do the self-management work of FH. The thesis consists of quantitative and qualitative ...
    • Impacts of the MHC class I-like XNC10 and innate-like T cells on tumor tolerance and rejection in the amphibian Xenopus 

      Banach, Maureen; Edholm, Eva-Stina Isabella; Gonzalez, Xavier; Benraiss, Abdellatif; Robert, Jaques (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-01)
      The conditions that lead to antitumor or protumor functions of natural killer T (NKT) cells against mammalian tumors are only partially understood. Therefore, insights into the evolutionary conservation of NKT and their analogs—innate-like T (iT) cells—may reveal factors that contribute to tumor eradication. As such, we investigated the amphibian <i>Xenopus laevis</i> iT cells and interacting MHC ...
    • Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk 

      Jansen, Iris E.; Savage, Jeanne E.; Watanabe, Kyoko; Bryois, Julien; Williams, Dylan M.; Steinberg, Stacy; Sealock, Julia; Karlsson, Ida K.; Hägg, Sara; Athanasiu, Lavinia; Voyle, Nicola; Proitsi, Petroula; Witoelar, Aree; Stringer, Sven; Aarsland, Dag; Almdahl, Ina Selseth; Andersen, Fred; Bergh, Sverre; Bettella, Francesco; Björnsson, Sigurbjörn; Brækhus, Anne; Bråthen, Geir; de Leeuw, Christiaan A.; Desikan, Rahul S.; Djurovic, Srdjan; Dumitrescu, Logan; Fladby, Tormod; Hohman, Timothy J.; Jónsson, Pálmi V.; Kiddle, Steven J; Rongve, Arvid; Saltvedt, Ingvild; Sando, Sigrid Botne; Selbæk, Geir; Shoai, Maryam; Skene, Nathan G.; Snædal, Jón G.; Stordal, Eystein; Ulstein, Ingun; Wang, Yunpeng; White, Linda Rosemary; Hardy, John; Hjerling-Leffler, Jens; Sullivan, Patrick; van der Flier, Wiesje M.; Dobson, Richard; Davis, Lea K; Stefánsson, Hreinn; Stefánsson, Kári; Pedersen, Nancy L; Ripke, Stephan; Andreassen, Ole Andreas; Posthuma, Danielle (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-07)
      Alzheimer’s disease (AD) is highly heritable and recent studies have identified over 20 disease-associated genomic loci. Yet these only explain a small proportion of the genetic variance, indicating that undiscovered loci remain. Here, we performed a large genome-wide association study of clinically diagnosed AD and AD-by-proxy (71,880 cases, 383,378 controls). AD-by-proxy, based on parental diagnoses, ...