Natural polyphenols, such as resveratrol (RES) or epicatechin (EPI), are attractive for treatments of various diseases, including vaginal infections and inflammation, because of their strong anti-oxidative and anti-inflammatory properties. However, their low solubility and consequent poor bioavailability limit their therapeutic uses. To overcome these limitations, a vaginal delivery system comprising ...

Å gi barn og unge mulighet til deltakelse i forskning om temaer som angår deres liv og levekår er viktig. Samtidig innebærer forskning med mindreårige deltakere særskilte forskningsetiske og metodiske utfordringer. De har rett til beskyttelse, og deres integritet må ivaretas. Det kan oppstå et spenningsforhold mellom barns og unges deltakelse og deres rett til beskyttelse, særlig i forskning om ...

Casestudien undersøker hvordan samlokalisering av nødmeldingssentralene til politi, brann og helse påvirker læring og utvikling av transaksjonsminnesystem (TMS) på operativt nivå horisontalt mellom etater. Datamaterialet er innhentet fra ni norske nødmeldingssentraler med ulike samarbeidsbetingelser og geografi og er kategorisert i modellene SAMLOK, SPREDT og NÆR. Analysen av kvalitative ...

Optical nanoscopy techniques can image intracellular structures with high specificity at sub-diffraction limited resolution, bridging the resolution gap between optical microscopy and electron microscopy. So far conventional nanoscopy lacks the ability to generate high throughput data, as the imaged region is small. Photonic chip-based nanoscopy has demonstrated the potential for imaging large areas, ...

We herein outline the rationale for a Swedish cohort consortium, aiming to facilitate greater use of Swedish cohorts for world-class research. Coordination of all Swedish prospective population-based cohorts in a common infrastructure would enable more precise research findings and facilitate research on rare exposures and outcomes, leading to better utilization of study participants’ data, better ...

LTX-401 is a novel oncolytic compound designed for the local treatment of solid tumors. In the present study, we have examined the applicability and efficacy of LTX-401 in a rat model JM1 hepatocellular carcinoma, with particular interest in its ability to induce antitumor immunity. LTX-401 induces necrotic cell death followed by the release of immunogenic cell death mediators such as high-mobility ...

What is the meaning of active ageing in the daily life of frail older people in need of comprehensive home-based care services? This chapter addresses this question using in-depth interviews with women and men aged 70-97 in Northern Norway. The chapter illustrates first, that some older women and men actually prefer to age actively <i>within their home</i> by doing activities such as reading books, ...

The chapter considered Thorstein Veblen’s description of conspicuous consumption in the context of consuming food while travelling. Travelogues from pre-industrial Korean society were used for the data in the chapter, employing critical discourse analysis. The identified meanings were subsequently reflected on Veblen’s conspicuous consumption. Two embedded notions of instrumental and intrinsic values ...

<p><i>Background/Aim - </i>Periodontal disease is one of the most prevalent diseases in the world. There is a scarcity of epidemiological studies of periodontal disease in Norway. The overall aim of this thesis was to assess the burden of periodontitis in an adult population, and to explore risk factors, as well as health-promoting factors related to the disease. <p><i>Methods - </i>The thesis is ...