Neuroblastoma is a malignancy arising from the developing sympathetic nervous system and the most common and deadly cancer of infancy. New therapies are needed to improve the prognosis for high-risk patients and to reduce toxicity and late effects. Spleen tyrosine kinase (SYK) has previously been identified as a promising drug target in various inflammatory diseases and cancers but has so far not ...

Educational practice needs to continuously update the curriculum in line with both current theoretical frameworks developed within academia and the lived reality of the coming generation. This article takes the student perspective on this issue, investigating a case from secondary music education in England. In 2015, Jessy McCabe initiated a successful campaign for the inclusion of women composers ...

The paper deals with jump generators with a convolution kernel. Assuming that the kernel decays either exponentially or polynomially, we prove a number of lower and upper bounds for the resolvent of such operators. In particular we focus on sharp estimates of the resolvent kernel for small values of the spectral parameter. We consider two applications of these results. First we obtain pointwise ...

Although murine models for studying the development of cardiac dysfunction in diabetes mellitus are well established, their reported cardiac phenotypes vary. These reported divergences may, in addition to the severity of different models, also be linked to the methods used for cardiac functional assessment. In the present study, we examined the functional changes using conventional transthoracic ...

<i>Objective</i>: Physical activity contributes to prevent serious diseases and ailments, and previous research indicates that lifestyle habits are likely to track from early childhood to adulthood. 90% of Norwegian children aged 1–5 are enrolled in preschools, and preschool staff can play an important role in children’s activity levels. This study’s aim was to identify whether any associations ...

Temaet for oppgaven er å vurdere bakgrunnen for at det jobbes med kvalitet og arbeidsmiljø i samme struktur. Undersøkelsen er gjort på Universitetssykehuset i Nord-Norge og er foretatt som en casestudie, der avdelinger fra både klinikk og senter er undersøkt. Hensikten med oppgaven er å undersøke hvorfor denne strategien ble bestemt implementert og se om det fungerer som tenkt. Jeg bruker instrumentell ...

I denne oppgaven har vi forsket på hva som førte til at et omsorgssenter reduserte sykefraværet sitt kraftig over en treårs periode. Formålet med oppgaven har vært å identifisere hva som ligger bak det reduserte sykefraværet, og vi har identifisert de konkrete tiltakene, drøftet hvilke som har hatt effekt, og deretter drøftet om dette kan overføres til andre virksomheter og eventuelt hvordan. Vi har ...

This thesis examines the incorporation of Indigenous Local Knowledge (ILK) in the environmental governance regime in the Mackenzie Valley, Northwest Territories, Canada. In the Mackenzie Valley, the incorporation of ILK in the Environmental Impact Assessment (EIA) and the regulatory processes is one of the distinctive features of environmental governance in the region. However, the depth of the use ...

Tema for oppgaven er samhandling, hva gjør at flere ledere opplever samhandlings om vanskelig. Jeg utgangspunkt i hvordan operative ledere i helse og omsorgstjenestene i kommunen opplever dette. Jeg belyser de utfordringer lederne møter på i lys av instrumentelt perspektiv, kulturelt perspektiv og myte perspektiv. Jeg undersøker forhold ved selve samhandlingsbegrepet og samhandling som metode, videre ...

This study explores engagement with Northern and Indigenous peoples and communities, using principles and practices that are currently being used within and outside of the nuclear energy sector. The project seeks to identify gaps in current nuclear energy engagement, explore the legal requirements for proponents, and provide recommendations for improved engagement with the Indigenous community in ...