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dc.contributor.authorde Weerd, Louis
dc.contributor.authorSjåvik, Kristin
dc.contributor.authorPedersen, Lars Kjelsberg
dc.contributor.authorWeum, Sven
dc.contributor.authorHennig, Rune
dc.date.accessioned2020-06-11T07:58:07Z
dc.date.available2020-06-11T07:58:07Z
dc.date.issued2020-01-20
dc.description.abstractThis article describes the triple use of autologous amnion graft as a new procedure in the treatment of myelomeningocele and in myelomeningocele with split cord malformation. The first amnion graft was used as a physical and mechanical barrier to protect the myelomeningocele (MMC) from desiccation and mechanical stress directly after birth. A second graft was used as a dura substitute to close the cerebrospinal fluid compartment. Autologous amnion seems to be the ideal dural graft for closure of an MMC and for an MMC with split cord malformation. A tension-free and watertight closure was obtained. With the epithelium side placed to the spinal cord and due to its beneficial effect on scar formation, the risk for tethering cord syndrome is reduced when using autologous amnion as a dural graft. The regenerative properties of autologous amnion may contribute to repair neural damage. Finally, a third amnion graft was placed beneath the perforator flap used to close the skin defect to provide a watertight barrier and to stimulate flap survival.en_US
dc.identifier.citationde Weerd L, Sjåvik K, Pedersen LK, Weum S, Hennig r. Triple use of autologous amnion graft in the treatment of meningomyelocele and split cord malformation. Plastic and reconstructive surgery. Global open. 2020;8:e2539(1):1-3en_US
dc.identifier.cristinIDFRIDAID 1808252
dc.identifier.doi10.1097/GOX.0000000000002539
dc.identifier.issn2169-7574
dc.identifier.urihttps://hdl.handle.net/10037/18514
dc.language.isoengen_US
dc.publisherLippincott, Williams & Wilkinsen_US
dc.relation.journalPlastic and reconstructive surgery. Global open
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2020 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700en_US
dc.subjectVDP::Medisinske Fag: 700en_US
dc.titleTriple use of autologous amnion graft in the treatment of meningomyelocele and split cord malformationen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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