Now showing items 1958-1977 of 10096

    • Definisjon av en lavrisikopopulasjon i fødselshjelpen : kan dette gjøre sammenligning mellom fødeinstitusjoner mer meningsfylt? 

      Nyegaard, Cecilie (Master thesis; Mastergradsoppgave, 2007)
      Det er ofte vanskelig å sammenlikne resultater fra norske fødeinstitusjoner fordi fødepopulasjonen kan være høyst forskjellig. Det kan derfor være ønskelig å definere en standard lavrisikopopulasjon som gjør at sammenligning mellom institusjoner blir mer meningsfylt. Med utgangspunkt i en studie fra Storbritannia ønsket vi å se om definisjon av en såkalt standardpopulasjon kan være relevant ...
    • Deformable liposomes for skin therapy with human epidermal growth factor: The effect of liposomal surface charge 

      Ternullo, Selenia; Basnet, Purusotam; Holsæter, Ann Mari; Flaten, Gøril Eide; de Weerd, Louis; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-07)
      The topical administration of exogenous human epidermal growth factor (hEGF) is a promising approach for improved chronic wound therapy. To develop therapeutically superior hEGF formulation, we prepared hEGF-containing neutral (NDLs), cationic (CDLs) and anionic (ADLs) deformable liposomes (DLs), respectively, since it is expected that the liposomal surface charge can affect both the liposomal ...
    • Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila 

      Jacomin, Anne-Claire; Gohel, Raksha; Hussain, Zunoon; Varga, Agnes; Maruzs, Tamas; Eddison, Mark; Sica, Margaux; Jain, Ashish; Moffat, Kevin G.; Johansen, Terje; Jenny, Andreas; Juhasz, Gabor; Nezis, Ioannis (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-14)
      Hunger drives food-seeking behaviour and controls adaptation of organisms to nutrient availability and energy stores. Lipids constitute an essential source of energy in the cell that can be mobilised during fasting by autophagy. Selective degradation of proteins by autophagy is made possible essentially by the presence of LIR and KFERQ-like motifs. Using in silico screening of Drosophila ...
    • Dekontaminering av pattedyrslakt ved bruk av damp eller varmt vann. Uttalelse fra Faggruppe for hygiene og smittestoffer i Vitenskapskomiteen for mattrygghet 

      Nesbakken, Truls; Christensen, Hardy; Skjerve, Eystein; Nygård, Karin Maria; Yazdankhah, Siamak Pour; Lunestad, Bjørn Tore; Kapperud, Georg; Lassen, Jørgen Fr; Robertson, Lucy; Olsvik, Ørjan; Tranulis, Michael A.; Tryland, Morten; Rimstad, Espen (Research report; Forskningsrapport, 2010-04-15)
      Mattilsynet har gitt VKM i oppgave å foreta en risikovurdering når det gjelder ”dekontaminering av pattedyrslakt ved bruk av varmt vann eller damp”. Da det er en bestemtdekontamineringsteknologi Mattilsynet ønsker utredet, velger faggruppen å bruke den mer presise betegnelsen ”overflatepasteurisering av slakt” som er i tråd med uttrykk og definisjoner som forskere innenfor dette området har benyttet ...
    • Delay of Dental Care: An Exploratory Study of Procrastination, Dental Attendance, and Self-Reported Oral Health 

      Steinvik, Lene Marita; Svartdal, Frode; Johnsen, Jan-Are Kolset (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-20)
      Delay of dental care is a problem for dental public health. The present study explored the relationship between procrastination and dental attendance, focusing on delay in seeking dental care. This hypothetical relation was compared to other avoidance-related factors affecting dental attendance. In addition, an inquiry into the reasons for delaying dental care was conducted. Students (n = 164) ...
    • Delayed clearance of triglyceride-rich lipoproteins in young, healthy obese subjects 

      Larsen, Maria Arlén; Goll, Rasmus; Lekhal, Samira; Moen, Odd S.; Florholmen, Jon (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-15)
      Obesity is associated with the metabolic syndrome. The aims were, first, to study the postprandial triglyceride clearance in young, healthy obese subjects and, second, to investigate if fasting triglycerides can predict delayed postprandial triglyceride clearance. Eighteen apparently healthy, obese subjects with no clinical signs of metabolic disturbances participated. Controls were age‐ and ...
    • Delayed leukocytosis after hard strength and endurance exercise. Aspects of regulatory mechanisms 

      Risøy, Bjørn Audun; Lappegård, Knut T.; Raastad, Truls; Hallén, Jostein; Bæverfjord, Kjersti; Kravdal, Astrid; Siebke, Else Marie; Benestad, Haakon B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2003-12-11)
      Background: During infections, polymorphonuclear neutrophilic granulocytes (PMN) are mobilized from their bone marrow stores, travel with blood to the affected tissue, and kill invading microbes there. The signal(s) from the inflammatory site to the marrow are unknown, even though a number of humoral factors that can mobilize PMN, are well known. We have employed a standardized, non-infectious ...
    • Delayed sleep phase syndrome and melatonin treatment: A meta-analysis 

      Engebråten, Carina Femoen (Master thesis; Mastergradsoppgave, 2014-05-02)
      Delayed sleep phase syndrome er en søvnforstyrrelse som oppstår blant barn og unge voksne, som forårsaker vanskeligheter med å fungere normalt på dagtid når søvn-våken rytmen er forskjøvet. Diagnosen er vanlig, men det er allikevel ingen standardiserte rettningslinjer for behandling. Forskning de siste årene har funnet ut at hormonet melatonin påvirker søvn og endring av søvn-våken syklusen hos ...
    • Deliberate reasoning is not affected by language 

      Mækelæ, Martin Jensen; Pfuhl, Gerit (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-31)
      <p><i>Background</i>: Millions of people use a second language every day. Does this have an effect on their decision-making? Are decisions in a second language more deliberate? Two mechanisms have been proposed: reduced emotionality or increased deliberation. Most studies so far used problems where both mechanisms could contribute to a foreign language effect. Here, we aimed to identify whether ...
    • Deliberation Decreases the Likelihood of Expressing Dominant Responses 

      Martiny-Huenger, Torsten; Bieleke, Maik; Doerflinger, Johannes T.; Stephensen, Matthew; Gollwitzer, Peter M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-11)
      Deliberation is commonly assumed to be a central characteristic of humans’ higher cognitive functions, and the responses following deliberation are attributed to mechanisms that are qualitatively different from lower-level associative or affectively driven responses. In contrast to this perspective, the current article’s aim is to draw attention to potential issues with making inferences about ...
    • Delivery is key: lessons learnt from developing splice-switching antisense therapies 

      Godfrey, Caroline; Desviat, Lourdes R.; Smedsrød, Bård; Piétri-Rouxel, France; Denti, Michela A.; Disterer, Petra; Lorain, Stéphanie; Nogales-Gadea, Gisela; Sardone, Valentina; Anwar, Rayan; El Andaloussi, Samir; Letho, Taavi; Khoo, Bernard; Brolin, Camilla; Mc Van Roon-Mom, Willeke; Goyenvalle, Aurélie; Aartsma-Rus, Annemieke; Arechavala-Gomeza, Virginia (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-13)
      The use of splice-switching antisense therapy is highly promising, with a wealth of pre-clinical data and numerous clinical trials ongoing. Nevertheless, its potential to treat a variety of disorders has yet to be realized. The main obstacle impeding the clinical translation of this approach is the relatively poor delivery of anti- sense oligonucleotides to target tissues ...
    • Delivery Room ST Segment Analysis to Predict Short Term Outcomes in Near-Term and Term Newborns 

      Linde, Jørgen Erland; Solevåg, Anne Lee; Eilevstjønn, Joar; Blacy, Ladislaus; Kidanto, Hussein; Ersdal, Hege Langli; Klingenberg, Claus Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-03)
      Background: ST-segment changes to the fetal electrocardiogram (ECG) may indicate fetal acidosis. No large-scale characterization of ECG morphology immediately after birth has been performed, but ECG is used for heart rate (HR) assessment. We aimed to investigate ECG morphology immediately after birth in asphyxiated infants, using one-lead dry-electrode ECG developed for HR measurement. Methods: ...
    • Delrapport 2 i prosjektet "Snøscooter og trafikksikkerhet" Feltarbeid blant brukere og tiltaksplan for forebygging av ulykker. 

      Mehus, Alf Gunnar; Germeten, Sidsel (Research report; Forskningsrapport, 2009)
    • The Delta III and Delta Xtend reverse shoulder arthroplasty. Risk of revision and failure mechanisms: a report on 3,650 cases from the Norwegian Arthroplasty Register 1994-2021 

      Hole, Randi Margrete; Fenstad, Anne Marie; Gjertsen, Jan-Erik; Hallan, Geir; Furnes, Ove Nord (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-15)
      Background - The Delta reverse shoulder arthroplasty (RSA) is commonly used worldwide and is the most frequently used RSA in Norway. The aim of this registry-based study was to report 10- and 20-year implant survival, risk of revision, and reasons for revision in 2 consecutive time periods for Delta III (1994-2010) and Delta Xtend (2007-2021) prostheses.<p> <p>Methods - We included 3650 primary ...
    • Demens og pårørendes situasjon 

      Moholt, Jill-Marit; Skaalvik, Mari Wolff (Chronicle; Kronikk, 2016-04-07)
    • Demenssykdom og omsorgsforskning 

      Hamran, Torunn; Normann, Hans Ketil; Fottland, Anne Serine (Chronicle; Kronikk, 2013)
      Risiko for sykdom og skader øker med stigende alder, og mange eldre får flere sykdommer, skader og funksjonsnedsettelse samtidig. Dette vil særlig gjelde for personer som utvikler demenssykdom. I Norge får årlig ca 10 000 personer en demenssykdom. Det er i dag om lag 70 000 med diagnosen. Ca 250 000 personer – både syke og pårørende – er berørt av sykdommen. Antall eldre over 75 år og spesielt de ...
    • Dementia Disease Initiation: Demographically adjusted norms based on Scandinavian samples and comparison with published norms from North America 

      Espenes, Johan Jacob (Doctoral thesis; Doktorgradsavhandling, 2023-12-14)
      <p><i>Background:</i> Norms are necessary for interpreting neuropsychological test scores. In Norway and Sweden, there is a lack of local norms on neuropsychological tests. Consequently, Scandinavians are frequently norm-referenced to participants from North America tested decades prior. However, factors such as time of assessment, language, population differences in average performance on cognitive ...
    • Dementia Disease Initiation: Identifying subjective cognitive decline (SCD) due to Alzheimer’s disease 

      Kirsebom, Bjørn-Eivind (Doctoral thesis; Doktorgradsavhandling, 2019-05-20)
      Background: Alzheimer’s disease (AD) may develop 10-15 years before onset of mild cognitive impairment (MCI). Early intervention may serve to halt or delay disease progression. Thus, there is a need to investigate early cognitive and biological markers to detect and track disease progression. Subjective cognitive decline (SCD) is an established risk-factor for AD. However, SCD is a common phenomenon ...
    • Demografisk utvikling og potensialet for uformell omsorg i Norge 

      Blix, Bodil Hansen; Stalsberg, Helge; Moholt, Jill-Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-11)
      Bakgrunn: Myndighetene har forventninger om at bidrag fra pårørende og frivillige i omsorg for hjemmeboende eldre skal opprettholdes på dagens nivå eller økes i fremtiden. I artikkelen undersøker vi potensialet for uformell omsorg med utgangspunkt i den demografiske utviklingen frem mot 2040. Metode: Med utgangspunkt i folketall fra 2018 og Statistisk sentralbyrås befolkningsframskrivinger 2018–2040 ...