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dc.contributor.authorWilliamson, Adele Kim
dc.contributor.authorDe Santi, Concetta
dc.contributor.authorAltermark, Bjørn
dc.contributor.authorKarlsen, Christian
dc.contributor.authorHjerde, Erik
dc.date.accessioned2017-01-09T13:42:18Z
dc.date.available2017-01-09T13:42:18Z
dc.date.issued2016
dc.description.abstractThe marine Arctic isolate Halomonas sp. R5-57 was sequenced as part of a bioprospecting project which aims to discover novel enzymes and organisms from low-temperature environments, with potential uses in biotechnological applications. Phenotypically, Halomonas sp. R5-57 exhibits high salt tolerance over a wide range of temperatures and has extra-cellular hydrolytic activities with several substrates, indicating it secretes enzymes which may function in high salinity conditions. Genome sequencing identified the genes involved in the biosynthesis of the osmoprotectant ectoine, which has applications in food processing and pharmacy, as well as those involved in production of polyhydroxyalkanoates, which can serve as precursors to bioplastics. The percentage identity of these biosynthetic genes from Halomonas sp. R5-57 and current production strains varies between 99 % for some to 69 % for others, thus it is plausible that R5-57 may have a different production capacity to currently used strains, or that in the case of PHAs, the properties of the final product may vary. Here we present the finished genome sequence (LN813019) of Halomonas sp. R5-57 which will facilitate exploitation of this bacterium; either as a whole-cell production host, or by recombinant expression of its individual enzymes.en_US
dc.identifier.citationStandards in Genomic Sciences 2016, 11:62en_US
dc.identifier.cristinIDFRIDAID 1395377
dc.identifier.doi10.1186/s40793-016-0192-4
dc.identifier.issn1944-3277
dc.identifier.urihttps://hdl.handle.net/10037/10114
dc.language.isoengen_US
dc.relation.projectIDNorges forskningsråd: 192123en_US
dc.rights.accessRightsopenAccessen_US
dc.subjectHalomonasen_US
dc.subjectGrowth temperatureen_US
dc.subjectSalt toleranceen_US
dc.subjectSecreted enzymesen_US
dc.subjectOsmolyteen_US
dc.subjectPolyhydroxyalkanoatesen_US
dc.subjectVDP::Matematikk og Naturvitenskap: 400::Kjemi: 440en_US
dc.subjectVDP::Mathematics and natural science: 400::Chemistry: 440en_US
dc.subjectVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470::Biokjemi: 476en_US
dc.subjectVDP::Mathematics and natural science: 400::Basic biosciences: 470::Biochemistry: 476en_US
dc.titleComplete genome sequence of Halomonas sp. R5-57en_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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