• Estimating the impact of indoor relative humidity on SARS-CoV-2 airborne transmission risk using a new modification of the Wells-Riley model 

      Aganovic, Amar; Bi, Yang; Cao, Guangyu; Drangsholt, Finn; Kurnitski, Jarek; Wargocki, Pawel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-23)
      A novel modified version of the Wells-Riley model was used to estimate the impact of relative humidity (RH) on the removal of respiratory droplets containing the SARS-CoV-2 virus by deposition through gravitational settling and its inactivation by biological decay; the effect of RH on susceptibility to SARS-CoV-2 was not considered. These effects were compared with the removal achieved by increased ...
    • Experimental study on the exposure level of surgical staff to SARS-CoV-2 in operating rooms with mixing ventilation under negative pressure 

      Bi, Yang; Aganovic, Amar; Mathisen, Hans Martin; Cao, Guangyu (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-21)
      The purpose of this study was to reveal the exposure level of surgical staff to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the patient's nose and wound during operations on COVID-19 patients. The tracer gas N<sub>2</sub>O is used to simulate SARS-CoV-2 from the patient's nose and wound. In this study, concentration levels of tracer gas were measured in the breathing zones of ...
    • Experimental Study on the Surgical Microenvironment in an Operating Room with Mixing Ventilation under Positive and Negative Pressure 

      Bi, Yang; Heggebø, Frida Josefine; Harsem, Trond Thorgeir; Mathisen, Hans Martin; Aganovic, Amar; Cao, Guangyu (Chapter; Bokkapittel, 2021)
      Due to the outbreak of Covid-19, negative pressure operating room (NPOR) are strongly recommended to be applied to prevent spreading virus from infected patients to adjacent rooms during surgery procedures. However, there have been few experimental studies on the effect of OR pressure difference on the surgical microenvironment. This study aims to experimentally investigate the airflow distribution ...
    • Experimental study on the surgical microenvironment in an operating room with mixing ventilation under positive and negative pressure 

      Bi, Yang; Josefine Heggebø, Frida; Harsem, Trond Thorgeir; Mathisen, Hans Martin; Aganovic, Amar; Cao, Guangyu (Chapter; Bokkapittel, 2021)
      Due to the outbreak of Covid-19, negative pressure operating room (NPOR) are strongly recommended to be applied to prevent spreading virus from infected patients to adjacent rooms during surgery procedures. However, there have been few experimental studies on the effect of OR pressure difference on the surgical microenvironment. This study aims to experimentally investigate the airflow distribution ...
    • Modeling the impact of indoor relative humidity on the infection risk of five respiratory airborne viruses 

      Aganovic, Amar; Bi, Yang; Cao, Guangyu; Kurnitski, Jarek; Wargocki, Pawel (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-07)
      With a modified version of the Wells-Riley model, we simulated the size distribution and dynamics of five airborne viruses (measles, influenza, SARS-CoV-2, human rhinovirus, and adenovirus) emitted from a speaking person in a typical residential setting over a relative humidity (RH) range of 20–80% and air temperature of 20–25 °C. Besides the size transformation of virus-containing droplets due to ...
    • New dose-response model and SARS-CoV-2 quanta emission rates for calculating the long-range airborne infection risk 

      Aganovic, Amar; Cao, Guangyu; Wargocki, Pawel; Kurnitski, Jarek (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-14)
      Predictive models for airborne infection risk have been extensively used during the pandemic, but there is yet still no consensus on a common approach, which may create misinterpretation of results among public health experts and engineers designing building ventilation. In this study we applied the latest data on viral load, aerosol droplet sizes and removal mechanisms to improve the Wells Riley ...
    • A systematic review of operating room ventilation 

      Sadrizadeh, Sasan; Aganovic, Amar; Bogdan, Anna; Wang, Cong; Afshari, Alireza; Hartmann, Anne; Croitoru, Cristiana; Khan, Amirul; Kriegel, Martin; Lind, Merethe; Liu, Zhijian; Melikov, Arsen; Mo, Jinhan; Rotheudt, Hansjörg; Yao, Runming; Zhang, Yixian; Abouali, Omid; Langvatn, Håkon; Sköldenberg, Olof; Cao, Guangyu (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-18)
      Ventilation systems are the primary way of eliminating airborne pathogenic particles in an operating room (OR). However, such systems can be complex due to factors such as different surgical instruments, diverse room sizes, various staff counts, types of clothing used, different surgical types and duration, medications, and patient conditions. OR ventilation should provide a thermally comfortable ...
    • Ventilation design conditions associated with airborne bacteria levels within the wound area during surgical procedures: a systematic review 

      Aganovic, Amar; Cao, Guangyu; Fečer, Tomáš; Ljungqvist, Bengt L.; Lytsy, Birgitta; Radtke, Andreas; Reinmüller, Berit; Traversari, Roberto A.A.L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-26)
      Without confirmation of the ventilation design conditions (typology and airflow rate), the common practice of identifying unidirectional airflow (UDAF) systems as equivalent to ultra-clean air ventilation systems may be misleading, but also any claims about the ineffectiveness of UDAF systems should be doubted. The aim of this review was to assess and compare ventilation system design conditions for ...
    • Zonal modeling of air distribution impact on the long-range airborne transmission risk of SARS-CoV-2 

      Aganovic, Amar; Cao, Guangyu; Kurnitski, Jarek; Melikov, Arsen; Wargocki, Pawel (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-28)
      A widely used analytical model to quantitatively assess airborne infection risk is the Wells-Riley model which is limited to complete air mixing in a single zone. However, this assumption tends not to be feasible (or reality) for many situations. This study aimed to extend the Wells-Riley model so that the infection risk can be calculated in spaces where complete mixing is not present. Some more ...