Knowledge base for the assessment of environmental risks by the use of genetically modified virus-vectored vaccines for domesticated animals. Scientific Opinion of the Panel on Microbial Ecology of the Norwegian Scientific Committee for Food Safety
VKM has appointed a working group consisting of members of the Panel on Microbial Ecology and the VKM secretariat to answer the request. The VKM Panel has reviewed and revised the draft prepared by the working group and finally approved the opinion.
This Report contains the findings of a desk study of current virus vectors used in GM virus vectored vaccines of domesticated livestock. A survey of the published literature for current knowledge in the area was undertaken with the aim of providing information relevant to the ERA of veterinary GM virus vectors (GM-VV). In identifying potential risk factors associated with vaccination of domesticated animals using GM-VV, focus was on the Norwegian environment, but relevant parallels were drawn from other European countries.