Browsing Artikler, rapporter og annet (kjemi) by Title

Now showing items 527-528 of 528

    • X-ray crystal structure of Vibrio alkaline phosphatase with the non-competitive inhibitor cyclohexylamine 

      Ásgeirsson, Bjarni; Markússon, Sigurbjörn; Hlynsdóttir, Sigríður S.; Helland, Ronny; Hjörleifsson, Jens G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-15)
      <i>Background</i> - <i>Para</i>-nitrophenyl phosphate, the common substrate for alkaline phosphatase (AP), is available as a cyclohexylamine salt. Here, we report that cyclohexylamine is a non-competitive inhibitor of APs.<br><br> <i>Methods</i> - Cyclohexylamine inhibited four different APs. Co-crystallization with the cold-active <i>Vibrio</i> AP (VAP) was performed and the structure solved.<br><br> ...

    • β-Octabromo- and β-Octakis(trifluoromethyl)isocorroles: New Sterically Constrained Macrocyclic Ligands 

      Kolle, Ekaney Thomas; Beavers, Christine M.; Gagnon, Kevin J.; Ghosh, Abhik (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-26)
      Presented herein is a study of the acid-induced demetalation of two sterically hindered copper corroles, Cu b-octabromomeso-triphenylcorrole (Cu[Br8TPC]) and b-octakis(trifluoromethyl)-meso-tris(p-methoxyphenyl)corrole (Cu[(CF3 )8TpOMePC]). Unlike reductive demetalation, which affords the free-base boctabromocorrole, demetalation of Cu[Br8TPC] under nonreductive conditions (CHCl3 /H2SO4 ) ...