During the last decade or so, scientists at the Norwegian Structural Biology Centre (NorStruct) have used the enzyme uracil DNA glycosylase (UDG) as a model system in the study of cold-adaptation, protein-DNA recognition and enzyme specificity. The cod UDG (cUDG) and human UDG (hUDG) are thoroughly biologically characterized and there are established well-functioning recombinant expression systems ...