Doktorgradsavhandlinger (NT-fak): Nye registreringer
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Optimizing pathology workflows: A practical deep learning approach for cell-level biomarker quantification
(Doctoral thesis; Doktorgradsavhandling, 2025-08-27)Computational pathology continues to advance through deep learning. However, interactive analysis of gigapixel whole slide images remains challenging due to high computational demands and long processing times. Variability in tissue morphology and staining quality further complicates automated cell detection and quantification in clinical workflows. In this study, we present an integrated and ... -
Towards more accurate and label-efficient Left Ventricle Automatic Measurements
(Doctoral thesis; Doktorgradsavhandling, 2025-08-21)<p>Accurate left ventricular (LV) linear measurements are critical for cardiac function assessment in echocardiography. However, manual measurements are time-consuming and prone to variability due to anatomical complexity and operator dependency. While deep learning (DL) models have automated landmark detection, existing fully automated B-mode approaches often produce inaccurate predictions caused ... -
Uncertainty and Representation Learning in Image Recognition: Advancing Deep Learning for Microfossil Analysis
(Doctoral thesis; Doktorgradsavhandling, 2025-08-20)Alongside the rapid development of deep learning, image recognition has achieved significant advances, with particularly promise within the supervised learning paradigm. While current models demonstrate strong predictive performance on benchmark datasets, deep neural networks often lack robustness, exhibiting unpredictable failures in operation. Challenges such as out-of-distribution data from unseen ... -
Towards general and effective antifouling surfaces – covalent surface attachment of antimicrobial peptides
(Doctoral thesis; Doktorgradsavhandling, 2025-08-26)<p>Healthcare-associated infections are of grave concern in healthcare facilities as these acquired infections pose a significant threat to the quality of life across the globe. Healthcare-associated infections are often related to the use of medical devices like catheters, joint prostheses, and implants. Medical devices are especially prone to bacterial growth, which can result in possible ... -
Constraining the environmental and biological controls on the geochemical composition of Neogloboquadrina pachyderma: Towards developing robust proxies for reconstructing polar surface ocean hydrography
(Doctoral thesis; Doktorgradsavhandling, 2025-08-13)<p>Rapid ongoing climate change includes warmer sea surface temperatures, salinity changes, reduced sea ice cover, and melting ice sheets in the polar regions. This has consequences for climate and society regionally and globally. However, there are large knowledge gaps regarding the sensitivity of these systems. Records of past changes in polar climate and ocean-cryosphere interactions can provide ... -
On the Future of Arctic Sea Ice - Projections, Dynamics, and Human Impacts
(Doctoral thesis; Doktorgradsavhandling, 2025-06-20)<p>Arctic sea ice (ASI) is a critical component of the Earth’s climate system, serving as both a regulator of energy exchange and a sensitive indicator of climate change. Over recent decades, ASI has experienced a dramatic decline in both extent and thickness, driven by rising global temperatures and amplified by Arctic feedback mechanisms. This decline is a key driver of Arctic amplification, a ... -
Device-based measurement of lifestyle-related variables from the hip
(Doctoral thesis; Doktorgradsavhandling, 2025-06-17)Physical activity epidemiology is the study of patterns, risks, and effects of physical activity within populations. It plays a crucial role in understanding how physical activity influences health outcomes, such as reducing the risk of chronic diseases like cardiovascular disease, diabetes, and obesity. An important prerequisite is the accurate measurement of physical activity, which can be assessed ... -
Study of the energy consumption and duration of a Cyber-Physical System reconfiguration in the Arctic Tundra: from experiments on real infrastructure to extensive simulations
(Doctoral thesis; Doktorgradsavhandling, 2025-05-23)Cyber-Physical systems (CPS) deployed in scarce-resource environments like the Arctic Tundra for in-situ and long-term observation face extreme conditions. Nodes deployed on the field are under a limited energy budget. To save energy and increase their lifetimes, nodes are forced to alternate between short uptime periods and long sleeping periods. Uptime schedules depend notably on observation tasks ... -
Tectonic evolution of the North Norwegian Caledonides in the North Troms region. A structural, metamorphic, geochemical and geochronological analysis of the Balsfjord Group and Nakkedal Nappe Complex as parts of the north Norwegian nappe assembly
(Doctoral thesis; Doktorgradsavhandling, 2025-05-22)This thesis presents new data for the geological units of the Balsfjord Group and Nakkedal Nappe Complex that are part of the North Norwegian Caledonides. The Balsfjord Group has been shown to feature a complex structural history including four stages of progressive deformation labelled as S0–1–S4 where S2 represents the main metamorphic foliation. It also exhibits a significant rotation of the ... -
Ultrasound & Photoacoustic Microscopy for Biomedical Applications
(Doctoral thesis; Doktorgradsavhandling, 2025-05-21)<p>Ultrasound and photoacoustic microscopy hold great promise for deep tissue imaging with high resolution, offering different applications in biological research. The primary aim of this thesis is to perform correlative photoacoustic and ultrasound microscopy experiments on various biological samples. <p>This thesis discusses multiple imaging modes, including A-scan, B-scan, and C-scan, each ... -
Stable spirocyclic nitroxide spin labels
(Doctoral thesis; Doktorgradsavhandling, 2025-03-28)Nitroxides are a class of organic radicals that exhibit remarkable stability under ambient conditions due to kinetic, thermodynamic, and electronic factors. Their unpaired electron and stability render nitroxides valuable as probes and polarisation transfer agents in spectroscopy and imaging techniques. In particular, electron paramagnetic resonance (EPR) spectroscopy extensively utilizes nitroxides ... -
Empirical Study and Modelling of Sea-Spray Parameters for Robust Marine Icing Estimation
(Doctoral thesis; Doktorgradsavhandling, 2025-03-20)Sea-spray icing poses a significant risk to maritime operations in Arctic and sub-Arctic regions, threatening the stability, safety, and efficiency of vessels and offshore structures. Current icing estimation models are constrained by limited data and are often tailored to specific vessels or structures. A critical challenge lies in accurately estimating spray flux, which is the amount of water ... -
Associations between dietary patterns and risk factors for cardiovascular disease
(Doctoral thesis; Doktorgradsavhandling, 2025-03-04)<p>In this thesis, the association between dietary patterns and risk factors for cardiovascular diseases was investigated using data from the seventh Tromsø Study (Tromsø7). A total of 21,083 individuals aged 40 years and older participated in Tromsø7. Approximately 10,000 of these participants completed 90% or more of the food frequency questionnaire. Their responses formed the foundation of our ... -
Compliance by Design in AI Systems – Towards Compliance with Data Protection Regulation, The AI Act, and Cybersecurity Regulations in AI System Development and Deployment
(Doctoral thesis; Doktorgradsavhandling, 2025-03-07)<p>"Without prejudice to" is a term frequently used in EU technology regulations. Regulation 2024/1689 (The Artificial Intelligence (AI) Act) is "without prejudice to" the General Data Protection Regulation (GDPR), and recent cybersecurity regulations such as the Network and Information Security (NIS) 2 Directive and the Cyber Resilience Act (CRA) are without prejudice to both the GDPR and the AI ... -
Investigation of Multilayers in Polar Mesospheric Summer Echoes
(Doctoral thesis; Doktorgradsavhandling, 2025-02-21)<p>Understanding the influence of the Sun and space on the Earth's atmosphere is of current interest, as it may be valuable in the context of global climate change research. Polar Mesospheric Summer Echoes (PMSE) are phenomenona that rely on the presence of ice particles, offering insights into the mesosphere's temperature and water vapor content. This thesis aimed to investigate PMSE in the upper ... -
Local-Scale Advanced Ship Predictor towards Enhanced Maritime Situation Awareness
(Doctoral thesis; Doktorgradsavhandling, 2025-02-18)With the introduction of autonomous and remotely-controlled ships, close vessel encounter can be associated with higher risk of collision or near-miss scenarios. To avoid these possible incidents, a higher level of situation awareness is required to support the respective decision-making process in maritime navigation. Advanced Ship Predictors (ASPs) are thus proposed to be a solution framework to ... -
Ocean Surface Current Uncertainty Quantification via Drift Modeling and Spaceborne Retrieved Radial Velocities
(Doctoral thesis; Doktorgradsavhandling, 2025-01-29)Ocean surface current is an essential ocean state variable in operational oceanography. They govern the movement of pollutants, microorganisms, heat, and salt across the ocean. Their dynamics shape marine ecosystems and influence climate patterns. Monitoring and accurately predicting ocean surface currents are essential for managing offshore pollution and its potential impacts on the shoreline, ... -
Model and Data Diagnosis under Limited Supervision in Modern AI
(Doctoral thesis; Doktorgradsavhandling, 2024-12-13)Deep Learning in modern Artificial Intelligence (AI) has witnessed unprecedented success on a variety of domains over the past decade, ranging from computer vision to natural language reasoning tasks. This success is owed primarily to the availability of large, annotated datasets, the existence of powerful mathematical models, and the mechanism to train large models on such data with advanced resources ... -
Intermittent fluctuations at the boundary of magnetically confined plasmas
(Doctoral thesis; Doktorgradsavhandling, 2024-11-29)This thesis presents a comprehensive analysis of a stochastic model for transport due to the motion of uncorrelated localized structures. The motivation for this model is found in the scrape-off layer (SOL) of magnetically confined plasmas, but its applicability extends to other turbulent or chaotic systems. This model provides a statistical framework to explore the implications of different transport ... -
Epidemiology Network Analysis
(Doctoral thesis; Doktorgradsavhandling, 2024-11-29)<p><i>Research questions</i> The primary objective of this doctoral dissertation is an explorative investigation into the social network dynamics within eight high schools, located in Tromsø and Balsfjord (North Norway), and the extent to which these dynamics contribute to the overall health and well-being of the students, such as in the context of infectious disease spread and the transmission of ...