Institutt for klinisk medisin: Nye registreringer
Viser treff 721-740 av 1804
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Surgery for herniated lumbar disc in private vs public hospitals: A pragmatic comparative effectiveness study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-04)<p><i>Background - </i>There is limited evidence on the comparative performance of private and public healthcare. Our aim was to compare outcomes following surgery for lumbar disc herniation (LDH) in private versus public hospitals. <p><i>Methods - </i>Data were obtained from the Norwegian registry for spine surgery. Primary outcome was change in Oswestry disability index (ODI) 1 year after surgery. ... -
Surgery for Extraforaminal Lumbar Disc Herniation: A Single Center Comparative Observational Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-13)<p><i>Background - </i>Surgery on extraforaminal lumbar disc herniation (ELDH) is a commonly performed procedure. Operating on this type of herniation is known to come with more difficulties than on the frequently seen paramedian lumbar disc herniation (PLDH). However, no comparative data are available on the effectiveness and safety of this operation. We sought out to compare clinical outcomes at ... -
Group mentorship for undergraduate medical students—a systematic review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-20)<p><i>Introduction - </i>Mentoring has become a prevalent educational strategy in medical education, with various aims. Published reviews of mentoring report very little on group-based mentorship programs. The aim of this systematic review was to identify group-based mentorship programs for undergraduate medical students and describe their aims, structures, contents and program evaluations. Based ... -
High spatially sensitive quantitative phase imaging assisted with deep neural network for classification of human spermatozoa under stressed condition
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-04)Sperm cell motility and morphology observed under the bright field microscopy are the only criteria for selecting a particular sperm cell during Intracytoplasmic Sperm Injection (ICSI) procedure of Assisted Reproductive Technology (ART). Several factors such as oxidative stress, cryopreservation, heat, smoking and alcohol consumption, are negatively associated with the quality of sperm cell and ... -
Genetic interaction between the non‐homologous end joining factors during B and T lymphocyte development: in vivo mouse models
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-12)Non‐homologous end joining (NHEJ) is the main DNA repair mechanism for the repair of double‐strand breaks (DSBs) throughout the course of the cell cycle. DSBs are generated in developing B and T lymphocytes during V(D)J recombination to increase the repertoire of B and T cell receptors. DSBs are also generated during the class switch recombination (CSR) process in mature B lymphocytes, providing ... -
The Master Study in Telemedicine and E-health at the University of Tromsø, Norway, 2005-2018
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020)In this paper we describe the Master Study in Telemedicine and E-health at the University of Tromsø, Norway. The study enrolled its first students in 2005 and was closed in 2018. We describe and discuss the background of the programme, its development and accomplishments and why it was closed. Hopefully, this narrative will be of use to other programmes focusing on e-health. -
Serum PTH is not a good marker for defining a threshold for vitamin D deficiency
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-01)<i>Objective</i>: In addition to its skeletal effects, vitamin D may also be important for health in general. It is uncertain what level of serum 25-hydroxyvitamin D (25(OH)D), marker of vitamin D status, is sufficient for these effects. With decreasing serum 25(OH)D levels there is an increase in serum PTH. The point at which this occurs has been considered as a threshold for vitamin D sufficiency. ... -
Randomised comparison of provisional side branch stenting versus a two-stent strategy for treatment of true coronary bifurcation lesions involving a large side branch: the Nordic-Baltic Bifurcation Study IV
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-19)<i>Background</i> - It is still uncertain whether coronary bifurcations with lesions involving a large side branch (SB) should be treated by stenting the main vessel and provisional stenting of the SB (simple) or by routine two-stent techniques (complex). We aimed to compare clinical outcome after treatment of lesions in large bifurcations by simple or complex stent implantation.<p> <p><i>Methods</i> ... -
Behandlingsrater for ryggkirurgi i Norge og Helse Nord 2014-18
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-23)<i>BAKGRUNN</i> - Formålet med denne studien var å undersøke om behandlingstilbudet innen ryggkirurgi i Helse Nord er i henhold til den vedtatte funksjonsfordelingen mellom sykehusene i regionen, og om det er geografisk variasjon i tilbudet. Vi undersøkte derfor behandlingsrater i Norge og Helse Nord, samt egendekning i Helse Nord, og vurderte aktiviteten i regionen.<p> <p><i>MATERIALE OG METODE</i> ... -
Clinical characterization of Helicobacter pylori infected patients 15 years after unsuccessful eradication
(Journal article; Tidsskriftartikkel, 2020-09-23)<i>Background and aims</i> - Patients that have failed therapy for Helicobacter pylori (H. pylori) infection are incompletely characterized. The aim of this study was to characterize a H. pylori treatment resistant cohort compared to the cohorts of newly diagnosed, earlier eradicated and non-infected.<p> <p><i>Material and methods</i> - Patients were selected from routine referrals to the Endoscopy ... -
A Survey on Cannabinoid Treatment of Pediatric Epilepsy Among Neuropediatricians in Scandinavia and Germany
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-24)<i>Objectives</i>: There is an increasing interest in cannabinoid-based products for the treatment of refractory pediatric epilepsy. However, a licensed cannabidiol (CBD) product was first approved for use by the European regulatory authorities in 2019. We aimed to obtain knowledge about clinical experience and attitudes toward cannabinoid use for epilepsy treatment among neuropediatricians in ... -
Room tilt illusion and subclavian steal - A case report
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-08)<i>Background</i> - Room tilt illusion (RTI) is a rare symptom of higher vestibular dysfunction, consisting of a transient vertical rotation of the visual scene in the sagittal or coronal plane, most often 90<sup>o</sup> or 180<sup>o</sup>, without any alteration in shape, size and color of objects.<br><br> <i>Case presentation</i> - A 63-year-old woman with a history of hypertension and chronic ... -
Increased calcium intake is associated lower serum 25-hydroxyvitamin D levels in subjects with adequate vitamin D intake: a population-based observational study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-02)<i>Background</i> - There are indications that an increased intake of calcium has a vitamin D sparing effect, which might be explained by a decreased catabolism of 25-hydroxyvitamin D (25(OH)D). However, there are only a few studies where this has been examined.<p> <p><i>Method</i> - In the seventh survey of the Tromsø study, serum 25(OH)D and parathyroid hormone were measured, and questionnaires ... -
Sudden caffeine withdrawal triggers migraine—A randomized controlled trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-10)<i>Objective</i>: Assessing the effects of caffeine withdrawal on migraine.<p> <p><i>Background</i>: The effects of caffeine withdrawal on migraineurs are at large unknown.<p> <p><i>Methods</i>: This was a randomized, double-blind, crossover study (NCT03022838), designed to enroll 80 adults with episodic migraine and a daily consumption of 300–800 mg caffeine. Participants substituted their ... -
Staphylococcus borealis sp. nov., isolated from human skin and blood
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-13)When analysing a large cohort of <i>Staphylococcus haemolyticus</i>, using whole-genome sequencing, five human isolates (four from the skin and one from a blood culture) with aberrant phenotypic and genotypic traits were identified. They were phenotypically similar with yellow colonies, nearly identical 16S rRNA gene sequences and initially speciated as <i>S. haemolyticus</i> based on 16S rRNA gene ... -
Dietary changes in early-stage breast cancer patients from pre-surgery and over the 12 months post-surgery
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-19)The time after a breast cancer diagnosis is a potential period for making positive dietary changes, but previous results are conflicting. The main aim of the present study was to study breast cancer patients’ dietary changes during the 12 months post-surgery and from 12 months pre-surgery to 12 months post-surgery with repeated administration of a 7-d pre-coded food diary and an FFQ, respectively. ... -
A Dynamic Method, Analysis, and Model of Short-Term Memory for Serial Order with Clinical Applications
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-06)This study examined the robustness of a traditional memory task when moved out of controlled traditional settings. A letter recall task was designed to be self-administered via a smart-device which assessed recall by participants’ writing their responses on the device. This enabled collection of both the letter recalled and the timing of this recall such that the temporal dynamics could be examined. ... -
Longterm Outcomes of Temporomandibular Joints in Juvenile Idiopathic Arthritis: 17 Years of Followup of a Nordic Juvenile Idiopathic Arthritis Cohort.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-01)<i>Objective</i> - To determine the prevalence of orofacial symptoms, dysfunctions, and deformities of the temporomandibular joint (TMJ) in juvenile idiopathic arthritis (JIA) 17 years after disease onset.<p> <p><i>Methods</i> - Drawn from a prospective, population-based Nordic JIA cohort with disease onset from 1997 to 2000, 420 consecutive cases were eligible for orofacial evaluation of TMJ ... -
Non-radiologist-performed point-of-care ultrasonography in paediatrics — European Society of Paediatric Radiology position paper
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-19)Non-radiologist point-of-care ultrasonography (US) is increasingly implemented in paediatric care because it is believed to facilitate a timely diagnosis, such as in ascites or dilated renal pelvicalyceal systems, and can be used to guide interventional procedures. To date, all policy statements have been published by non-radiologic societies. The European Society of Paediatric Radiology hereby ... -
Chronic nonbacterial osteomyelitis — clinical and magnetic resonance imaging features
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-09)<i>Background</i> - Chronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory bone disorder. Little information exists on the use of imaging techniques in CNO.<p> <p><i>Materials and methods</i> - We retrospectively reviewed clinical and MRI findings in children diagnosed with CNO between 2012 and 2018. Criteria for CNO included unifocal or multifocal inflammatory bone lesions, symptom ...