Blar i forfatter Artikler, rapporter og annet (informatikk) "Perduca, Vittorio"
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Predicting breast cancer metastasis from whole-blood transcriptomic measurements
Holsbø, Einar; Perduca, Vittorio; Bongo, Lars Ailo; Lund, Eiliv; Birmelé, Etienne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-20)<i>Objective</i> - In this exploratory work we investigate whether blood gene expression measurements predict breast cancer metastasis. Early detection of increased metastatic risk could potentially be life-saving. Our data comes from the Norwegian Women and Cancer epidemiological cohort study. The women who contributed to these data provided a blood sample up to a year before receiving a breast ... -
Shrinkage estimation of rate statistics
Holsbø, Einar Jakobsen; Perduca, Vittorio (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-08)This paper presents a simple shrinkage estimator of rates based on Bayesian methods. Our focus is on crime rates as a motivating example. The estimator shrinks each town’s observed crime rate toward the country-wide average crime rate according to town size. By realistic simulations we confirm that the proposed estimator outperforms the maximum likelihood estimator in terms of global risk. We also ...