• Predicting breast cancer metastasis from whole-blood transcriptomic measurements 

      Holsbø, Einar; Perduca, Vittorio; Bongo, Lars Ailo; Lund, Eiliv; Birmelé, Etienne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-20)
      <i>Objective</i> - In this exploratory work we investigate whether blood gene expression measurements predict breast cancer metastasis. Early detection of increased metastatic risk could potentially be life-saving. Our data comes from the Norwegian Women and Cancer epidemiological cohort study. The women who contributed to these data provided a blood sample up to a year before receiving a breast ...
    • Shrinkage estimation of rate statistics 

      Holsbø, Einar Jakobsen; Perduca, Vittorio (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-08)
      This paper presents a simple shrinkage estimator of rates based on Bayesian methods. Our focus is on crime rates as a motivating example. The estimator shrinks each town’s observed crime rate toward the country-wide average crime rate according to town size. By realistic simulations we confirm that the proposed estimator outperforms the maximum likelihood estimator in terms of global risk. We also ...