• Characterization of the degree of food processing in the European Prospective Investigation into Cancer and Nutrition: Application of the Nova classification and validation using selected biomarkers of food processing 

      Huybrechts, Inge; Rauber, Fernanda; Nicolas, Geneviève; Casagrande, Corinne; Kliemann, Nathalie; Wedekind, Roland; Biessy, Carine; Scalbert, Augustin; Touvier, Mathilde; Aleksandrova, Krasimira; Jakszyn, Paula; Skeie, Guri; Bajracharya, Rashmita; Boer, Jolanda M. A.; Borné, Yan; Chajes, Veronique; Dahm, Christina C.; Dansero, Lucia; Guevara, Marcela; Heath, Alicia K.; Ibsen, Daniel B.; Papier, Keren; Katzke, Verena; Kyrø, Cecilie; Masala, Giovanna; Molina-Montes, Esther; Robinson, Oliver J. K.; Santiuste de Pablos, Carmen; Schulze, Matthias B.; Simeon, Vittorio; Sonestedt, Emily; Tjønneland, Anne; Tumino, Rosario; van der Schouw, Yvonne T.; Verschuren, W. M. Monique; Vozar, Beatrice; Winkvist, Anna; Gunter, Marc J.; Monteiro, Carlos A.; Millett, Christopher; Levy, Renata Bertazzi (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-16)
      Background: Epidemiological studies have demonstrated an association between the degree of food processing in our diet and the risk of various chronic diseases. Much of this evidence is based on the international Nova classification system, which classifies food into four groups based on the type of processing: (1) Unprocessed and minimally processed foods, (2) Processed culinary ingredients, ...
    • Comparing Calculated Nutrient Intakes Using Different Food Composition Databases: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort 

      Van Puyvelde, Heleen; Perez-Cornago, Aurora; Casagrande, Corinne; Nicolas, Geneviève; Versele, Vickà; Skeie, Guri; Schulze, Matthias B.; Johansson, Ingegerd; Huerta, José María; Oliverio, Andreina; Ricceri, Fulvio; Halkjær, Jytte; Etxezarreta, Pilar Amiano; Van Herck, Koen; Weiderpass, Elisabete; Gunter, Marc J.; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-23)
      This study aimed to compare calculated nutrient intakes from two different food composition databases using data from the European prospective investigation into cancer and nutrition (EPIC) cohort. Dietary intake data of the EPIC cohort was recently matched to 150 food components from the U.S. nutrient database (USNDB). Twenty-eight of these nutrients were already included in the EPIC nutrient ...
    • Consumption of Fish and Long-chain n-3 Polyunsaturated Fatty Acids Is Associated With Reduced Risk of Colorectal Cancer in a Large European Cohort 

      Aglago, Elom Kouassivi; Huybrechts, Inge; Murphy, Neil; Casagrande, Corinne; Nicolas, Geneviève; Pischon, Tobias; Fedirko, Veronika; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Fournier, Agnès; Katzke, Verena Andrea; Kühn, Tilman; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Lasheras, Cristina; Agudo, Antonio; Sanchez, Maria-Jose; Amiano, Pilar; Huerta, Jose Maria; Ardanaz, Eva; Perez-Cornago, Aurora; Trichopoulou, Antonia; Karakatsani, Anna; Martimianaki, Georgia; Bueno-De-Mesquita, Bas; May, Anne; Derksen, Jeroen W.G.; Hellstrand, Sophie; Ohlsson, Bodil; Wennberg, Maria; Van Guelpen, Bethany; Skeie, Guri; Brustad, Magritt; Weiderpass, Elisabete; Cross, Amanda J.; Ward, Heather; Riboli, Elio; Norat, Teresa; Chajes, Veronique; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-25)
      Background & Aims - There is an unclear association between intake of fish and long-chain n-3 polyunsaturated fatty acids (n-3 LC-PUFAs) and colorectal cancer (CRC). We examined the association between fish consumption, dietary and circulating levels of n-3 LC-PUFAs, and ratio of n-6:n-3 LC-PUFA with CRC using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. ...
    • Consumption of ultra-processed foods associated with weight gain and obesity in adults: A multi-national cohort study 

      Cordova, Reynalda; Kliemann, Nathalie; Huybrechts, Inge; Rauber, Fernanda; Vamos, Eszter P.; Levy, Renata Bertazzi; Wagner, Karl-Heinz; Viallon, Vivian; Casagrande, Corinne; Nicolas, Geneviève; Dahm, Christina Catherine; Zhang, Jie; Halkjær, Jytte; Tjønneland, Anne; Boutron-Ruault, Marie-Chiristine; Mancini, Francesca Romana; Laouali, Nasser; Katzke, Verena; Srour, Bernard; Jannasch, Franziska; Schulze, Matthias B; Masala, Giovanna; Grioni, Sara; Panico, Salvatore; van der Schouw, Yvonne T; Derksen, Jeroen W.G.; Rylander, Charlotta; Skeie, Guri; Jakszyn, Paula; Rodríguez-Barranco, Miguel; Huerta, José María; Barricarte, Aurelio; Brunkwall, Louise; Ramne, Stina; Bodén, Stina; Perez-Cornago, Aurora; Heath, Alicia K; Vineis, Paolo; Weiderpass, Elisabete; Monteiro, Carlos Augusto; Gunter, Marc J; Millett, Christopher J.; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
      Background - There is a worldwide shift towards increased consumption of ultra-processed foods (UPF) with concurrent rising prevalence of obesity. We examined the relationship between the consumption of UPF and weight gain and risk of obesity.<p> <p>Methods - This prospective cohort included 348 748 men and women aged 25–70 years. Participants were recruited between 1992 and 2000 from 9 European ...
    • Dietary intake of total, heme and non-heme iron and the risk of colorectal cancer in a European prospective cohort study 

      Aglago, Elom K.; Cross, Amanda J.; Riboli, Elio; Fedirko, Veronika; Hughes, David J.; Fournier, Agnes; Jakszyn, Paula; Freisling, Heinz; Gunter, Marc J.; Dahm, Christina C.; Overvad, Kim; Tjønneland, Anne; Kyrø, Cecilie; Boutron-Ruault, Marie-Christine; Rothwell, Joseph A.; Severi, Gianluca; Katzke, Verena; Srour, Bernard; Schulze, Matthias B.; Wittenbecher, Clemens; Palli, Domenico; Sieri, Sabina; Pasanisi, Fabrizio; Tumino, Rosario; Ricceri, Fulvio; Bueno-de-Mesquita, Bas; Derksen, Jeroen W. G.; Skeie, Guri; Jensen, Torill; Lukic, Marko; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Barricarte, Aurelio; Ericson, Ulrika; van Guelpen, Bethany; Papier, Keren; Knuppel, Anika; Casagrande, Corinne; Huybrechts, Inge; Heath, Alicia K.; Tsilidis, Konstantinos K.; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-09)
      Background - Iron is an essential micronutrient with differing intake patterns and metabolism between men and women. Epidemiologic evidence on the association of dietary iron and its heme and non-heme components with colorectal cancer (CRC) development is inconclusive.<p> <p>Methods - We examined baseline dietary questionnaire-assessed intakes of total, heme, and non-heme iron and CRC risk in the ...
    • Dietary intake of trans fatty acids and breast cancer risk in 9 European countries 

      Matta, Michèle; Huybrechts, Inge; Biessy, Carine; Casagrande, Corinne; Yammine, Sahar; Fournier, Agnès; Olsen, Karina Standahl; Lukic, Marco; Gram, Inger Torhild; Ardanaz, Eva; Sánchez, Maria-José; Dossus, Laure; Fortner, Renée T.; Srour, Bernard; Jannasch, Franziska; Schulze, Matthias B.; Amiano, Pilar; Agudo, Antonio; Colorado-Yohar, Sandra; Guirós, J. Ramón; Tumino, Rosario; Panico, Salvatore; Masala, Giovanna; Pala, Valeria; Sacerdote, Carlotta; Tjønneland, Anne; Olsen, Anja; Dahm, Christina C.; Rosendahl, Ann H.; Borgquist, Signe; Wennberg, Maria; Heath, Alicia K.; Aune, Dagfinn; Schmidt, Julie; Weiderpass, Elisabete; Chajes, Veronique; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-30)
      Background - Trans fatty acids (TFAs) have been hypothesised to influence breast cancer risk. However, relatively few prospective studies have examined this relationship, and well-powered analyses according to hormone receptor-defined molecular subtypes, menopausal status, and body size have rarely been conducted.<p> <p>Methods - In the European Prospective Investigation into Cancer and Nutrition ...
    • Dietary intakes of dioxins and polychlorobiphenyls (PCBs) and breast cancer risk in 9 European countries 

      Fiolet, Thibault; Casagrande, Corinne; Nicolas, Geneviève; Horvath, Zsuzsanna; Frenoy, Pauline; Weiderpass, Elisabete; Katzke, Verena; Kaaks, Rudolf; Rodriguez-Barranco, Miguel; Panico, Salvatore; Sacerdote, Carlotta; Manjer, Jonas; Sonestedt, Emily; Grioni, Sara; Agudo, Antonio; Rylander, Charlotta; Nøst, Therese Haugdahl; Skeie, Guri; Tjønneland, Anne; Raaschou-Nielsen, Ole; Ardanaz, Eva; Amiano, Pilar; Dolores Chirlaque López, María; Schulze, Matthias B.; Wennberg, Maria; Harlid, Sophia; Cairat, Manon; Kvaskoff, Marina; Huybrechts, Inge; Romana Mancini, Francesca (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-26)
      Background: Dioxins and polychlorobiphenyls (PCBs) are persistent organic pollutants that have demonstrated endocrine disrupting properties. Several of these chemicals are carcinogenic and positive associations have been suggested with breast cancer risk. In general population, diet represents the main source of exposure.<p><p> Methods: Associations between dietary intake of 17 dioxins and 35 PCBs ...
    • Evaluation of protein and amino acid intake estimates from the EPIC dietary questionnaires and 24-h dietary recalls using different food composition databases 

      Iguacel, Isabel; Perez-Cornago, Aurora; Schmidt, Julie A.; Van Puyvelde, Heleen; Travis, Ruth; Casagrande, Corinne; Nicolas, Genevieve; Riboli, Elio; Weiderpass, Elisabete; Ardanaz, Eva; Barricarte, Aurelio; Bodén, Stina; Bruno, Eleonora; Ching-López, Ana; Aune, Dagfinn; Jensen, Torill; Ericson, Ulrika; Johansson, Ingergerd; Ma Huerta, José; Katzke, Verena; Kühn, Tilman; Sacerdote, Carlotta; Schulze, Matthias B.; Skeie, Guri; Ramne, Stina; Ward, Heather; Gunter, Marc J.; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-20)
      Background and aims: This study aimed to expand the European Prospective Investigation into Cancer and Nutrition (EPIC) nutrient database (ENDB) by adding amino acid (AA) values, using the U.S. nutrient database (USNDB). Additionally, we aimed to evaluate these new protein and AA intake estimates from the EPIC dietary questionnaires (DQ) and 24- h dietary recalls (24-HDR) using different matching ...
    • Food biodiversity and total and cause-specific mortality in 9 European countries: An analysis of a prospective cohort study 

      Hanley-Cook, Giles T.; Huybrechts, Inge; Biessy, Carine; Remans, Roseline; Kennedy, Gina; Deschasaux-Tanguy, Mélanie; Murray, Kris A.; Touvier, Mathilde; Skeie, Guri; Kesse-Guyot, Emmanuelle; Argaw, Alemayehu; Casagrande, Corinne; Nicolas, Geneviève; Vineis, Paolo; Millett, Christopher J.; Weiderpass, Elisabete; Ferrari, Pietro; Dahm, Christina C.; Bueno-De-Mesquita, H. Bas; Sandanger, Torkjel M; Ibsen, Daniel B.; Freisling, Heinz; Ramne, Stina; Jannasch, Franziska; van der Schouw, Yvonne T.; Schulze, Matthias B.; Tsilidis, Konstantinos K.; Tjønneland, Anne; Ardanaz, Eva; Bodén, Stina; Cirera, Lluís; Gargano, Giuliana; Halkjær, Jytte; Jakszyn, Paula; Johansson, Ingegerd; Katzke, Verena; Masala, Giovanna; Panico, Salvatore; Rodriguez-Barranco, Miguel; Sacerdote, Carlotta; Srour, Bernard; Tumino, Rosario; Riboli, Elio; Gunter, Marc J.; Jones, Andrew D.; Lachat, Carl (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-18)
      Background<p> <p>Food biodiversity, encompassing the variety of plants, animals, and other organisms consumed as food and drink, has intrinsic potential to underpin diverse, nutritious diets and improve Earth system resilience. Dietary species richness (DSR), which is recommended as a crosscutting measure of food biodiversity, has been positively associated with the micronutrient adequacy of diets ...
    • Food processing and cancer risk in Europe: results from the prospective EPIC cohort study 

      Kliemann, Nathalie; Rauber, Fernanda; Bertazzi Levy, Renata; Viallon, Vivian; Vamos, Eszter P; Cordova, Reynalda; Freisling, Heinz; Casagrande, Corinne; Nicolas, Genevieve; Aune, Dagfinn; Tsilidis, Konstantinos K; Heath, Alicia; Schulze, Matthias B; Jannasch, Franziska; Srour, Bernard; Kaaks, Rudolf; Rodriguez-Barranco, Miguel; Tagliabue, Giovanna; Agudo, Antonio; Panico, Salvatore; Ardanaz, Eva; Chirlaque, María-Dolores; Vineis, Paolo; Tumino, Rosario; Perez-Cornago, Aurora; Andersen, Julie Louise Munk; Tjønneland, Anne; Skeie, Guri; Weiderpass, Elisabete; Monteiro, Carlos Augusto; Gunter, Marc J; Millett, Christopher; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-06)
      Background - Food processing has been hypothesised to play a role in cancer development; however, data from large-scale epidemiological studies are scarce. This study investigated the association between dietary intake according to amount of food processing and risk of cancer at 25 anatomical sites using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) study.<p> ...
    • Mycotoxin Exposure and Renal Cell Carcinoma Risk: An Association Study in the EPIC European Cohort 

      Claeys, Liesel; De Saeger, Sarah; Scelo, Ghislaine; Biessy, Carine; Casagrande, Corinne; Nicolas, Genevieve; Korenjak, Michael; Fervers, Beatrice; Heath, Alicia K.; Krogh, Vittorio; Luján-Barroso, Leila; Castilla, Jesús; Ljungberg, Börje; Rodriguez-Barranco, Miguel; Ericson, Ulrika; Santiuste, Carmen; Catalano, Alberto; Overvad, Kim; Brustad, Magritt; Gunter, Marc J.; Zavadil, Jiri; De Boevre, Marthe; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-30)
      Background: Mycotoxins have been suggested to contribute to a spectrum of adverse health effects in humans, including at low concentrations. The recognition of these food contaminants being carcinogenic, as co-occurring rather than as singularly present, has emerged from recent research. The aim of this study was to assess the potential associations of single and multiple mycotoxin exposures with ...
    • Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study 

      Deschasaux, Mélanie; Huybrechts, Inge; Murphy, Neil; Julia, Chantal; Hercberg, Serge; Srour, Bernard; Kesse-Guyot, Emmanuelle; Latino-Martel, Paule; Biessy, Carine; Casagrande, Corinne; Jenab, Mazda; Ward, Heather; Weiderpass, Elisabete; Dahm, Christina C.; Overvad, Kim; Kyrø, Cecilie; Olsen, Anja; Affret, Aurélie; Boutron-Ruault, Marie-Christine; Mahamat-Saleh, Yahya; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Schwingshackl, Lukas; Bamia, Christina; Peppa, Eleni; Trichopoulou, Antonia; Masala, Giovanna; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Hjartåker, Anette; Rylander, Charlotta; Skeie, Guri; Ramõn Quirõs, Jose; Jakszyn, Paula; Salamanca-Fernández, Elena; Huerta, José María; Ardanaz, Eva; Amiano, Pilar; Ericson, Ulrika; Sonestedt, Emily; Huseinovic, Ena; Johansson, Ingegerd; Khaw, Kay-Tee; Wareham, Nick; Bradbury, Kathryn E.; Perez-Cornago, Aurora; Tsilidis, Konstantinos K.; Ferrari, Pietro; Riboli, Elio; Gunter, Mark J.; Touvier, Mathilde (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-18)
      <p><i>Background - </i>Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling system to reflect the nutritional quality of food products. The Nutri-Score, a five-colour nutrition label, is derived from the Nutrient Profiling System of the British ...
    • Ultra-processed foods, adiposity and risk of head and neck cancer and oesophageal adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition study: a mediation analysis 

      Morales-Berstein, Fernanda; Biessy, Carine; Viallon, Vivian; Goncalves-Soares, Ana; Casagrande, Corinne; Hémon, Bertrand; Kliemann, Nathalie; Cairat, Manon; Blanco Lopez, Jessica; Al Nahas, Aline; Chang, Kiara; Vamos, Eszter; Rauber, Fernanda; Bertazzi Levy, Renata; Barbosa Cunha, Diana; Jakszyn, Paula; Ferrari, Pietro; Vineis, Paolo; Masala, Giovanna; Catalano, Alberto; Sonestedt, Emily; Borné, Yan; Katzke, Verena; Bajracharya, Rashmita; Agnoli, Claudia; Guevara, Marcela; Heath, Alicia; Radoï, Loredana; Mancini, Francesca; Weiderpass Vainio, Elisabete; Huerta, José María; Sánchez, María-José; Tjønneland, Anne; Kyrø, Cecilie; Schulze, Matthias B.; Skeie, Guri; Lukic, Marko; Braaten, Tonje Bjørndal; Gunter, Marc; Millett, Christopher; Agudo, Antonio; Brennan, Paul; Borges, M. Carolina; Richmond, Rebecca C.; Richardson, Tom G.; Davey Smith, George; Relton, Caroline L.; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-22)
      Purpose - To investigate the role of adiposity in the associations between ultra-processed food (UPF) consumption and head and neck cancer (HNC) and oesophageal adenocarcinoma (OAC) in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.<p> <p>Methods - Our study included 450,111 EPIC participants. We used Cox regressions to investigate the associations between the ...