• High circulating levels of the homeostatic chemokines CCL19 and CCL21 predict mortality and disease severity in Covid-19 

      Tveita, Anders Aune; Murphy, Sarah Louise Mikalsen; Holter, Jan Cato; Kildal, Anders Benjamin; Michelsen, Annika Elisabet; Lerum, Tøri Vigeland; Kaarbø, Mari; Heggelund, Lars; Holten, Aleksander Rygh; Finbråten, Ane-Kristine; Muller, Karl Erik; Mathiessen, Alexander; Bøe, Simen; Fevang, Børre; Granerud, Beathe Kiland; Tonby, Kristian; Lind, Andreas; Dudman, Susanne; Nezvalova-Henriksen, Katerina; Müller, Fredrik; Skjønsberg, Ole Henning; Trøseid, Marius; Barratt-Due, Andreas; Riise, Anne Margarita Dyrhol; Aukrust, Pål; Halvorsen, Bente Evy; Dahl, Tuva Børresdatter; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-25)
      Background. Immune dysregulation is a major factor in the development of severe coronavirus disease 2019 (COVID-19). The homeostatic chemokines CCL19 and CCL21 have been implicated as mediators of tissue inflammation, but data on their regulation in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is limited. We thus investigated the levels of these chemokines in COVID-19 ...