Blar i forfatter Det helsevitenskapelige fakultet "Ellefsen, Stian"

Viser treff 1-3 av 3

    • Chronic obstructive pulmonary disease does not impair responses to resistance training 

      Mølmen, Knut Sindre; Hammarström, Jens Konrad Daniel; Falch, Gunnar Slettaløkken; Grundtvig, Morten; Koll, Lise; Hanestadhaugen, Marita; Khan, Yusuf; Ahmad, Rafi; Malerbakken, Bente; Rødølen, Tore Jørgen; Lien, Roger; Rønnestad, Bent; Raastad, Truls; Ellefsen, Stian (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-06)
      <i>Background</i> - Subjects with chronic obstructive pulmonary disease (COPD) are prone to accelerated decay of muscle strength and mass with advancing age. This is believed to be driven by disease-inherent systemic pathophysiologies, which are also assumed to drive muscle cells into a state of anabolic resistance, leading to impaired abilities to adapt to resistance exercise training. Currently, ...

    • Normalization of gene expression data revisited: the three viewpoints of the transcriptome in human skeletal muscle undergoing load-induced hypertrophy and why they matter 

      Khan, Yusuf; Hammarström, Daniel; Ellefsen, Stian; Ahmad, Rafi (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-18)
      Background - The biological relevance and accuracy of gene expression data depend on the adequacy of data normalization. This is both due to its role in resolving and accounting for technical variation and errors, and its defining role in shaping the viewpoint of biological interpretations. Still, the choice of the normalization method is often not explicitly motivated although this choice may be ...

    • Vitamin D3 supplementation does not enhance the effects of resistance training in older adults 

      Mølmen, Knut Sindre; Hammarström, Jens Konrad Daniel; Pedersen, Karianne; Lie, Anne Cecilie Lian; Steile, Ragnvald B.; Nygård, Håvard; Khan, Yusuf; Hamarsland, Håvard; Koll, Lise; Hanestadhaugen, Marita; Eriksen, Atle Lie; Grindaker, Eirik; Whist, Jon Elling; Buck, Daniel; Ahmad, Rafi; Strand, Tor Arne; Rønnestad, Bent R.; Ellefsen, Stian (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-31)
      Background: Lifestyle therapy with resistance training is a potent measure to counteract age-related loss in muscle strength and mass. Unfortunately, many individuals fail to respond in the expected manner. This phenomenon is particularly common among older adults and those with chronic diseases (e.g. chronic obstructive pulmonary disease, COPD) and may involve endocrine variables such as vitamin ...