• Serum Matrix Metalloproteinase 7 and accelerated glomerular filtration rate decline in a general non-diabetic population 

      Enoksen, Inger Therese T.; Svistounov, Dmitri; Norvik, Jon Viljar; Stefansson, Vidar Tor Nyborg; Solbu, Marit Dahl; Eriksen, Bjørn Odvar; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
      Background. Age-related reduction of glomerular filtration rate (GFR) is a major contributor to the global chronic kidney disease (CKD) epidemic. We investigated whether baseline serum levels of the pro-fibrotic matrix metalloproteinase 2 (MMP2), MMP7 and their inhibitor, tissue inhibitor of metalloproteinase 1 (TIMP1), which mediates fibrosis development in aging animals, were associated with ...