Enoksen, Inger Therese T.; Svistounov, Dmitri; Norvik, Jon Viljar; Stefansson, Vidar Tor Nyborg; Solbu, Marit Dahl; Eriksen, Bjørn Odvar; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
Background. Age-related reduction of glomerular filtration
rate (GFR) is a major contributor to the global chronic kidney
disease (CKD) epidemic. We investigated whether baseline serum levels of the pro-fibrotic matrix metalloproteinase 2
(MMP2), MMP7 and their inhibitor, tissue inhibitor of
metalloproteinase 1 (TIMP1), which mediates fibrosis development in aging animals, were associated with ...