Blar i forfatter Det helsevitenskapelige fakultet "Fabbri, Muller"

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    • 17β-estradiol promotes extracellular vesicle release and selective miRNA loading in ERα-positive breast cancer 

      Drula, Rares; Pardini, Barbara; Fu, Xiao; De Los Santos, Mireia Cruz; Jurj, Ancuta; Pang, Lan; El-Daly, Sherien M.; Fabris, Linda; Knutsen, Erik; Dragomir, Mihnea P.; Bayraktar, Recep; Li, Yongfeng; Chen, Meng; Del Vecchio, Filippo; Berland, Léa; Dae, Jessica; Fan, Daniel; Shimizu, Masayoshi; Tran, Anh M.; Barzi, Mercedes; Pioppini, Carlotta; Gutierrez, Angelica M.; Ivan, Cristina; Meas, Salyna; Hall, Carolyn S.; Alahari, Suresh K.; Berindan-Neagoe, Ioana; Fabbri, Muller; Lucci, Anthony; Arun, Banu; Anfossi, Simone; Calin, George A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-30)
      The causes and consequences of abnormal biogenesis of extracellular vesicles (EVs) are not yet well understood in malignancies, including in breast cancers (BCs). Given the hormonal signaling dependence of estrogen receptor–positive (ER+) BC, we hypothesized that 17β-estradiol (estrogen) might influence EV production and microRNA (miRNA) loading. We report that physiological doses of 17β-estradiol ...

    • Disclosing quantitative RT-PCR raw data during manuscript submission: a call for action 

      Untergasser, Andreas; Hellemans, Jan; Pfaffl, Michael W.; Ruijter, Jan M.; van den Hoff, Maurice J. B.; Dragomir, Mihnea P.; Adamoski, Douglas; Dias, Sandra Martha Gomes; Reis, Rui Manuel; Ferracin, Manuela; Dias-Neto, Emmanuel; Marsh, Ian; Kubista, Mikael; Fabbri, Muller; Goel, Ajay; Slabý, Ondřej; Knutsen, Erik; Chen, Baoqing; Negrini, Massimo; Mimori, Koshi; Pichler, Martin; Papatriantafyllou, Maria; Anfossi, Simone; Schmittgen, Thomas D.; Huggett, Jim; Bustin, Stephen; Vandesompele, Jo; Calin, George A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-14)
      Accuracy and transparency of scientific data are becoming more and more relevant with the increasing concern regarding the evaluation of data reproducibility in many research areas. This concern is also true for quantifying coding and noncoding RNAs, with the remarkable increase in publications reporting RNA profiling and sequencing studies. To address the problem, we propose the following ...