• C-reactive protein point-of-care testing for safely reducing antibiotics for acute exacerbations of chronic obstructive pulmonary disease: The PACE RCT 

      Francis, Nick; Gillespie, David; White, Patrick; Bates, Janine; Lowe, Rachel; Sewell, Bernadette; Phillips, Rhiannon; Stanton, Helen; Kirby, Nigel; Wootton, Mandy; Thomas-Jones, Emma; Hood, Kerenza; Llor, Carl; Cals, Jochen; Melbye, Hasse; Naik, Gurudutt; Gal, Micaela; Fitzsimmons, DF; Alam, Mohammed Fasihul; Riga, Evgenia; Cochrane, Ann; Butler, Christopher C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03)
      Background - Most patients presenting with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in primary care are prescribed antibiotics, but these may not be beneficial, and they can cause side effects and increase the risk of subsequent resistant infections. Point-of-care tests (POCTs) could safely reduce inappropriate antibiotic prescribing and antimicrobial resistance.<p> ...