• Adding marrow adiposity and cortical porosity to femoral neck areal bone mineral density improves the discrimination of women with nonvertebral fractures from controls 

      Zebaze, Roger; Osima, Marit; Bui, Minh; Lukic, Marko; Wang, Xiaofang; Ghasem-Zadeh, Ali; Eriksen, Erik Fink; Vais, Angela; Shore-Lorenti, Catherine; Ebeling, Peter R.; Seeman, Ego; Bjørnerem, Åshild (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-18)
      Advancing age is accompanied by a reduction in bone formation and remodeling imbalance, which produces microstructural deterioration. This may be partly caused by a diversion of mesenchymal cells towards adipocytes rather than osteoblast lineage cells. We hypothesized that microstructural deterioration would be associated with an increased marrow adiposity, and each of these traits would be independently ...
    • Measurement of cortical porosity of the proximal femur improves identification of women with nonvertebral fragility fractures 

      Ahmed, Luai Awad; Shigdel, Rajesh; Joakimsen, Ragnar Martin; Eldevik, Odd Petter; Eriksen, Erik Fink; Ghasem-Zadeh, Ali; Bala, Yohann; Zebaze, Roger; Seeman, Ego; Bjørnerem, Åshild (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-16)
      Summary We tested whether cortical porosity of the proximal femur measured using StrAx1.0 software provides additional information to areal bone mineral density (aBMD) or Fracture Risk Assessment Tool (FRAX) in differentiating women with and without fracture. Porosity was associated with fracture independent of aBMD and FRAX and identified additional women with fractures than by osteoporosis or ...