• Associations of inner retinal layers with risk of incident dementia: An individual participant data analysis of four prospective cohort studies 

      van der Heide, Frank C. T.; Khawaja, Anthony; Berendschot, Tos T. J. M.; Littlejohns, Thomas J.; Kuźma, Elżbieta; Luben, Robert; Patel, Praveen J.; Foster, Paul J.; Bertelsen, Geir; von Hanno, Therese; Johnsen, Bente; Schirmer, Henrik; Rebouças, Sara C. L.; Grasset, Leslie; Delcourt, Cécile; Helmer, Catherine; Stehouwer, Coen D. A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-08)
      INTRODUCTION - Our main objective was to investigate whether retinal neurodegeneration, estimated from lower thickness of inner retinal layers, was associated with incident all-cause dementia and Alzheimer's disease (AD).<p> <p>METHODS - We performed an individual participant data meta-analysis using unpublished data from four prospective cohort studies with a total of 69,955 participants (n = ...
    • Trajectories of recall memory as predictive of hearing impairment: A longitudinal cohort study 

      Maharani, Asri; Dawes, Piers; Nazroo, James; Tampubolon, Gindo; Pendleton, Neil; Bertelsen, Geir; Cosh, Suzanne; Cougnard-Grégoire, Audrey; Delcourt, Cécile; Constantinidou, Fofi; Goedegebure, Andre; Helmer, Catherine; Arfan Ikram, M; Klaver, Caroline C.W.; Leroi, Iracema; Meester-Smor, Magda; Nae, Virginie; Oosterloo, Neelke; Schirmer, Henrik; Tiemeier, Henning; von Hanno, Therese (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-18)
      <i>Objectives</i> - Accumulating evidence points to a relationship between hearing function and cognitive ability in later life. However, the exact mechanisms of this relationship are still unclear. This study aimed to characterise latent cognitive trajectories in recall memory and identify their association with subsequent risk of hearing impairment.<p> <p><i>Methods</i> - We analysed data from ...