Blar i forfatter Det helsevitenskapelige fakultet "Kessel, Christoph"
-
Inflammatory Biomarkers Can Differentiate Acute Lymphoblastic Leukemia with Arthropathy from Juvenile Idiopathic Arthritis Better Than Standard Blood Tests
Brix, Ninna; Glerup, Mia; Foell, Dirk; Kessel, Christoph; Wittkowski, Helmut; Berntson, Lillemor; Fasth, Anders; Nielsen, Susan; Nordal, Ellen Berit; Rygg, Marite; Hasle, Henrik; Herlin, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-04)Objective - To evaluate the predictive value of biomarkers of inflammation like phagocyte-related S100 proteins and a panel of inflammatory cytokines in order to differentiate the child with acute lymphoblastic leukemia (ALL) from juvenile idiopathic arthritis (JIA).<p> <p>Study design - In this cross-sectional study, we measured S100A9, S100A12, and 14 cytokines in serum from children with ALL ... -
A novel serum calprotectin (MRP8/14) particle-enhanced immuno-turbidimetric assay (sCAL turbo) helps to differentiate systemic juvenile idiopathic arthritis from other diseases in routine clinical laboratory settings
Foell, Dirk; Saers, Melanie; Park, Carolin; Brix, Ninna; Glerup, Mia; Kessel, Christoph; Wittkowski, Helmut; Hinze, Claas; Berntson, Lillemor; Fasth, Anders; Myrup, Charlotte; Nordal, Ellen Berit; Rygg, Marite; Hasle, Henrik; Albertsen, Birgitte Klug; Herlin, Troels; Holzinger, Dirk; Niederberger, Christian; Schlüter, Bernhard (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-25)Background Differential diagnosis in children with signs of unprovoked inflammation can be challenging. In particular, differentiating systemic juvenile idiopathic arthritis (SJIA) from other diagnoses is difficult. We have recently validated the complex of myeloid-related proteins 8/14 (MRP8/14, also known as S100A8/A9 complex or serum calprotectin) as a helpful biomarker supporting the diagnosis ...