• Tumor-associated macrophages and macrophage-related immune checkpoint expression in sarcomas 

      Dancsok, Amanda R.; Gao, Dongxia; Lee, Anna F.; Steigen, Sonja Eriksson; Blay, Jean-Yves; Thomas, David M.; Maki, Robert G.; Nielsen, Torsten O.; Demicco, Elizabeth G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-12)
      Early trials for immune checkpoint inhibitors in sarcomas have delivered mixed results, and efforts to improve outcomes now look to combinatorial strategies with novel immunotherapeutics, including some that target macrophages. To enhance our understanding of the sarcoma immune landscape, we quantified and characterized tumor-associated macrophage infiltration and expression of the targetable ...