• High Expression of IRS-1, RUNX3 and SMAD4 Are Positive Prognostic Factors in Stage I–III Colon Cancer 

      Selven, Hallgeir; Rasmussen Busund, Lill-Tove; Andersen, Sigve; Pedersen, Mona Irene; Lombardi, Ana Paola Giometti; Kilvær, Thomas Karsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-24)
      Colon cancer is a common malignancy and a major contributor to human morbidity and mortality. In this study, we explore the expression and prognostic impact of IRS-1, IRS-2, RUNx3, and SMAD4 in colon cancer. Furthermore, we elucidate their correlations with miRs 126, 17-5p, and 20a-5p, which are identified as potential regulators of these proteins. Tumor tissue from 452 patients operated for stage ...