Blar i forfatter Det helsevitenskapelige fakultet "Mayini, Justin"

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    • “The effect of 48-weeks azithromycin therapy on levels of soluble biomarkers associated with HIV-associated chronic lung disease” 

      Hameiri-Bowen, Dan; Yindom, Louis-Marie; Sovershaeva, Evgeniya; Bandason, Tsitsi; Mayini, Justin; M Rehman, Andrea; Simms, Victoria; Gift Ngwira, Lucky; Flagestad, Trond; Gutteberg, Tore Jarl; McHugh, Grace; Abbas Ferrand, Rashida; Rowland-Jones, Sarah L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-20)
      Objectives - HIV-associated immune activation contributes to chronic lung disease (CLD) in children and adolescents living with HIV. Azithromycin has immunomodulatory and anti-microbial properties that may be useful for treating HIV-associated CLD (HCLD). This study describes the effect of azithromycin on expression of plasma soluble biomarkers in children and adolescents with HCLD.<p> <p>Methods ...

    • Prevalence and antimicrobial resistance profiles of respiratory microbial flora in African children with HIV-associated chronic lung disease 

      Abotsi, Regina E.; Nicol, Mark P.; McHugh, Grace; Simms, Victoria; Rehman, Andrea M.; Barthus, Charmaine; Mbhele, Slindile; Moyo, Brewster Wisdom; Ngwira, Lucky Gift; Mujuru, Hilda A.; Makamure, Beauty; Mayini, Justin; Odland, Jon Øyvind; Ferrand, Rashida A.; Dube, Felix S. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-25)
      <b>Background</b> HIV-associated chronic lung disease (CLD) is common among children living with HIV (CLWH) in sub-Saharan Africa, including those on antiretroviral therapy (ART). However, the pathogenesis of CLD and its possible association with microbial determinants remain poorly understood. We investigated the prevalence, and antibiotic susceptibility of <i>Streptococcus pneumoniae </i>(SP), ...