Now showing items 1-3 of 3

    • Characterization of novel precursor miRNAs using next generation sequencing and prediction of miRNA targets in Atlantic halibut 

      Bizuayehu, Teshome; Fernandes, Jorge; Johansen, Steinar Daae; Babiak, Igor (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      microRNAs (miRNAs) are implicated in regulation of many cellular processes. miRNAs are processed to their mature functional form in a step-wise manner by multiple proteins and cofactors in the nucleus and cytoplasm. Many miRNAs are conserved across vertebrates. Mature miRNAs have recently been characterized in Atlantic halibut (Hippoglossus hippoglossus L.). The aim of this study was to identify and ...
    • Differential expression patterns of conserved miRNAs and isomiRs during Atlantic halibut development 

      Bizuayehu, Teshome; Lanes, Carlos Fredrico Ceccon; Furmanek, Tomasz; Karlsen, Bård Ove; Fernandes, Jorge; Johansen, Steinar; Babiak, Igor (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      MicroRNAs (miRNAs) play a major role in animal ontogenesis. Size variants of miRNAs, isomiRs, are observed along with the main miRNA types, but their origin and possible biological role are uncovered yet. Developmental profiles of miRNAs have been reported in few fish species only and, to our knowledge, differential expressions of isomiRs have not yet been shown during fish development. Atlantic ...
    • Temperature during early development has long-term effects on microRNA expression in Atlantic cod 

      Bizuayehu, Teshome Tilahun; Johansen, Steinar D; Puvanendran, Velmurugu; Toften, Hilde; Babiak, Igor (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-17)
      Background: Environmental temperature has serious implications in life cycle of aquatic ectotherms. Understanding the molecular mechanisms of temperature acclimation and adaptation of marine organisms is of the uttermost importance for ecology, fisheries, and aquaculture, as it allows modeling the effects of global warming on population dynamics. Regulatory molecules are major modulators of acclimation ...