Blar i forfatter Det helsevitenskapelige fakultet "Crossley, Kelly J."

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    • Efficacy of Intravenous, Endotracheal, or Nasal Adrenaline Administration During Resuscitation of Near-Term Asphyxiated Lambs 

      Songstad, Nils Thomas; Klingenberg, Claus; McGillick, Erin V.; Polglase, Graeme R.; Zahra, Valerie; Schmölzer, Georg M.; Davis, Peter G.; Hooper, Stuart B.; Crossley, Kelly J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-02)
      <i>Objectives</i>: Neonatal resuscitation guidelines recommend administering intravenous (IV) adrenaline if bradycardia persists despite adequate ventilation and chest compressions (CC). Rapid IV access is challenging, but little evidence exists for other routes of administration. We compared IV, endotracheal (ET), and intranasal routes for adrenaline administration during resuscitation of asphyxiated ...

    • Single sustained inflation followed by ventilation leads to rapid cardiorespiratory recovery but causes cerebral vascular leakage in asphyxiated near-term lambs 

      Sobotka, Kristina S.; Hooper, Stuart B.; Crossley, Kelly J.; Ong, Tracey; Schmölzer, Georg M.; Barton, Samantha K.; McDougall, Annie R.A.; Miller, Suzie L.; Tolcos, Mary; Klingenberg, Claus; Polglase, Graeme R. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016)
      Background A sustained inflation (SI) rapidly restores cardiac function in asphyxic, bradycardic newborns but its effects on cerebral haemodynamics and brain injury are unknown. We determined the effect of different SI strategies on carotid blood flow (CaBF) and cerebral vascular integrity in asphyxiated near-term lambs. Methods Lambs were instrumented and delivered at 139 ± 2 d gestation ...