Blar i forfatter Det helsevitenskapelige fakultet "Lorenz, Susanne"

Viser treff 1-2 av 2

    • High number of kinome-mutations in non-small cell lung cancers associated with reduced immune response and poor relapse-free survival 

      Helland, Åslaug; Brustugun, Odd Terje; Nakken, Sigve; Halvorsen, Ann Rita; Dønnem, Tom; Bremnes, Roy M.; Busund, Lill-Tove; Sun, Jinchang; Lorenz, Susanne; Solberg, Steinar; Jørgensen, Lars Hilmar; Vodak, Daniel; Myklebost, Ola; Hovig, Eivind; Meza, Leonardo Zepeda (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-07)
      Lung cancer is the leading cause of cancer related death, and the past years’ improved insight into underlying molecular events has significantly improved outcome for specific subsets of patients. In particular, several new therapies that target protein kinases have been implemented, and many more are becoming available. We have investigated lung cancer specimens for somatic mutations in a targeted ...

    • Novel GTF2I-PDGFRB and IKZF1-TYW1 fusions in pediatric leukemia with normal karyotype 

      Panagopoulos, Ioannis; Brunetti, Marta; Stoltenberg, Margrethe; Strandabø, Rønnaug; Staurseth, Julie; Andersen, Kristin; Kostolomov, Ilya; Hveem, Tarjei Sveinsgjerd; Lorenz, Susanne; Nystad, Tove Anita; Flægstad, Trond; Micci, Francesca; Heim, Sverre (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-29)
      <i>Background</i> - Many cases of acute lymphoblastic leukemia (ALL) carry visible acquired chromosomal changes of pathogenetic, diagnostic, and prognostic importance. Nevertheless, from one-fourth to half of newly diagnosed ALL patients have no visible chromosomal changes detectable by G-banding analysis at diagnosis. The introduction of powerful molecular methodologies has shown that many ...