Now showing items 1-1 of 1

    • Enterococcus faecium TIR-Domain Genes Are Part of a Gene Cluster Which Promotes Bacterial Survival in Blood 

      Wagner, Theresa; James Peter, Jessin Janice; Paganelli, Fernanda; Willems, Rob J.L.; Askarian, Fatemeh; Pedersen, Torunn Annie; Top, Janetta; de Haas, Carla; van strijp, Jos A. G.; Johannessen, Mona; Hegstad, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-03)
      <i>Enterococcus faecium</i> has undergone a transition to a multidrug-resistant nosocomial pathogen. The population structure of <i>E. faecium</i> is characterized by a sharp distinction of clades, where the hospital-adapted lineage is primarily responsible for bacteremia. So far, factors that were identified in hospital-adapted strains and that promoted pathogenesis of nosocomial <i>E. faecium</i> ...