Blar i forfatter Det helsevitenskapelige fakultet "Truedsson, Lennart"
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Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population
Gaya de Costa, Mariana; Poppelaars, Felix; van Kooten, Cees; Mollnes, Tom Eirik; Tedesco, Francesco; Würzner, Reinhard; Trouw, Leendert A.; Truedsson, Lennart; Daha, Mohamed R.; Roos, Anja; Seelen, Marc A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-20)<p><i>Introduction</i>: The complement system is essential for an adequate immune response. Much attention has been given to the role of complement in disease. However, to better understand complement in pathology, it is crucial to first analyze this system under different physiological conditions. The aim of the present study was therefore to investigate the inter-individual variation in complement ... -
The assessment of serum-mediated phagocytosis of necrotic material by polymorphonuclear leukocytes to diagnose and predict the clinical features of systemic lupus erythematosus: An observational longitudinal study
Compagno, Michele; Gullstrand, Birgitta; Eilertsen, Gro Østli; Nilsson, Jan Åke; Lood, Christian; Jönsen, Andreas; Truedsson, Lennart; Sturfelt, Gunnar; Bengtsson, Anders A (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-10)Background: Serum-mediated phagocytosis of antibody- and complement-opsonized necrotic cell material (NCM) by polymorphonuclear leukocytes can be quantified by using a flow cytometry–based assay. The phagocytosis of necrotic cell material (PNC) assay parallels the well-known lupus erythematosus cell test. In this study, we aimed to investigate the diagnostic accuracy of the assay and the relationship ... -
Clinical phenotype associations with various types of anti-dsDNA antibodies in patients with recent onset of rheumatic symptoms. Results from a multicentre observational study
Compagno, Michele; Rekvig, Ole Petter; Bengtsson, Anders; Sturfeld, Gunnar; Heegaard, Niels H. H.; Jönsen, Andreas; Jacobsen, Rasmus S.; Eilertsen, Gro Østli; Fenton, Christopher Graham; Truedsson, Lennart; Nossent, Johannes C; Jacobsen, Søren (Journal article; Tidsskriftartikkel, 2014)