Blar i forfatter Det helsevitenskapelige fakultet "Vodak, Daniel"

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    • High number of kinome-mutations in non-small cell lung cancers associated with reduced immune response and poor relapse-free survival 

      Helland, Åslaug; Brustugun, Odd Terje; Nakken, Sigve; Halvorsen, Ann Rita; Dønnem, Tom; Bremnes, Roy M.; Busund, Lill-Tove; Sun, Jinchang; Lorenz, Susanne; Solberg, Steinar; Jørgensen, Lars Hilmar; Vodak, Daniel; Myklebost, Ola; Hovig, Eivind; Meza, Leonardo Zepeda (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-07)
      Lung cancer is the leading cause of cancer related death, and the past years’ improved insight into underlying molecular events has significantly improved outcome for specific subsets of patients. In particular, several new therapies that target protein kinases have been implemented, and many more are becoming available. We have investigated lung cancer specimens for somatic mutations in a targeted ...