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norskDet helsevitenskapelige fakultet: Nye registreringer
Viser treff 1021-1040 av 10983
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Biochemical and Cellular Characterization of the Function of Fluorophosphonate-Binding Hydrolase H (FphH) in Staphylococcus aureus Support a Role in Bacterial Stress Response
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-12)The development of new treatment options for bacterial infections requires access to new targets for antibiotics and antivirulence strategies. Chemoproteomic approaches are powerful tools for profiling and identifying novel druggable target candidates, but their functions often remain uncharacterized. Previously, we used activity-based protein profiling in the opportunistic pathogen Staphylococcus ... -
Emergence of vancomycin-resistant enterococci from vancomycin susceptible enterococci in hospitalized patients under antimicrobial therapy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-19)Objectives: Enterococci are opportunistic pathogens with plastic genomes that evolve, acquire, and transmit antimicrobial-resistant determinants such as vancomycin resistance clusters. While vancomycinresistant enterococci (VRE) have emerged as successful nosocomial pathogens, the mechanism by which vancomycin-susceptible enterococci (VSE) transform to VRE in hospitalized patients remains ... -
Perspective: Dimensions of Environment and Health in Arctic Communities
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-12)In the Arctic, environment and health are linked in myriad ways. A key emphasis has been on numerous long-lived contaminants in traditional foods, particularly marine mammals, and their well-documented impacts on human, animal and environmental health (“One health approach”). More recent concerns for Indigenous communities focus on the (side) effects of the switch to a modern, processed diet, which ... -
Long-Term Results After Surgery for Degenerative Cervical Myelopathy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-20)BACKGROUND AND OBJECTIVES: Degenerative cervical myelopathy (DCM) is a frequent cause of spinal cord dysfunction, and surgical treatment is considered safe and effective. Long-term results after surgery are limited. This study investigated long-term clinical outcomes through data from the Norwegian registry for spine surgery.<p> <p>METHODS: Patients operated at the university hospitals serving ... -
Exploring Online Health Information Seeking Behaviour (OHISB) among young adults: A scoping review protocol
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-30)<p><i>Introduction</i> In recent years, information technology and social media have experienced unprecedented growth, particularly in the Nordic countries. However, there is a noticeable lack of comprehensive understanding regarding the latest research findings on online health information seeking behaviour (OHISB) among young adults (18 to >30). There is a need to conduct an updated review to ... -
Å være veileder i "praksisvinden"-utfordringer og didaktiske implikasjoner for praksisveilederutdanningen
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-01)Studien undersøker praksisveilederes utfordringer i veiledning av studenter i helse - og sosialfagutdanninger. Studien er en kvalitativ tekstanalyse. Datamaterialet er 72 eksamensbesvarelser fra praksisveiledere som gjennomførte praksisveilederutdanning. Resultatene viser at praksisveilederne har mange utfordringer; intrapersonlige-, interpersonlige- og strukturelle utfordringer. Hovedkategoriene ... -
Follow-Up of Patients With Axial Spondyloarthritis in Specialist Health Care With Remote Monitoring and Self-Monitoring Compared With Regular Face-to-Face Follow-Up Visits (the ReMonit Study): Protocol for a Randomized, Controlled Open-Label Noninferiority Trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-27)Background: Patients with chronic inflammatory joint diseases such as axial spondyloarthritis have traditionally received regular follow-up in specialist health care to maintain low disease activity. The follow-up has been organized as prescheduled face-to-face visits, which are time-consuming for both patients and health care professionals. Technology has enabled the remote monitoring of disease ... -
Description of the prehospital emergency healthcare system in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-23)Background: Norway has a long coastline, steep mountains, and wide fjords, which presents some challenges to the prehospital emergency healthcare system. In recent years, the prehospital emergency medical services (EMS) have undergone significant changes, structurally, in terms of professionalisation of the services and in the education level of the personnel. In this article, we aim to describe the ... -
Incidence of bleeding and recurrence in isolated distal deep vein thrombosis: findings from the Venous Thrombosis Registry in Østfold Hospital
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-30)Background - Isolated distal deep vein thrombosis (IDDVT) is a common presentation of deep vein thrombosis. There are limited data on the long-term risk of recurrence after IDDVT.<p> <p>Objectives - We aimed to determine the short- and long-term incidence of venous thrombosis (VTE) recurrence after cessation of anticoagulation and the 3-month incidence of bleeding during anticoagulant treatment ... -
Exploring Adolescents’ Attitudes Toward Mental Health Apps: Concurrent Mixed Methods Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-15)Background: Adolescence is a critical time in which many psychological disorders develop. Mental health promotion is important, especially during this period. In recent years, an increasing number of mobile apps geared toward mental health promotion and preventing mental illness have been developed specifically for adolescents, with the goal of strengthening their mental health and well-being.< ... -
Serum Markers of Neuronal Damage and Astrocyte Activity in Patients with Chronic Epilepsy: Elevated Levels of Glial Fibrillary Acidic Protein
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-07)Objectives. Blood-brain barrier (BBB) dysfunction is one of the key pathogenic mechanisms in the development of epilepsy. There is therefore an increasing need to identify BBB biomarkers as these will have prognostic and therapeutic implications. The purpose of this study was to assess the levels of the BBB permeability markers, glial fibrillary acidic protein (GFAP), neuron-specific enolase ... -
Nasjonal anbefaling for utredning og behandling av døgnrytmelidelser
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023)Nasjonal kompetansetjeneste for søvnsykdommer (fra 2023: Nasjonalt senter for søvnmedisin) nedsatte høsten 2022 en arbeidsgruppe for å utvikle en nasjonal anbefaling for utredning og behandling av døgnrytmelidelser. Gruppen bestod av personer med ulik yrkesbakgrunn (allmennlege, psykolog, psykiater, klinisk nevrofysiolog, fysiolog, sykepleier), som alle har forskningskompetanse innen fagområdet. ... -
Long-Term Follow-Up of Orthognathic Surgery in 19 Patients with Juvenile Idiopathic Arthritis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-30)Objectives: Dentofacial deformity following juvenile idiopathic arthritis with temporomandibular joint involvement is associated with functional, aesthetic, and psychosocial impairment. Surgical treatment may involve combinations of orthognathic surgery. The aims of this retrospective study were to assess orofacial symptoms, functional and aesthetic status, and stability after orthognathic ... -
Kunnskapsoppsummering og klassifisering av tiltaket: Flyt
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-12)Bakgrunn: Flyt er et livsmestringsprogram for elever på 10. trinn som har til hensikt å gjøre deltakere bedre rustet til å gjennomføre videregående skole. Programmet er et styrkebasert gruppetiltak for ungdom i risiko for å droppe ut fra videregående, men ungdom uten kjent risiko inkluderes også. For elever omfatter tiltaket totalt 80 timer med organiserte aktiviteter fordelt på helg- og kveldssamlinger ... -
Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST): a multicentre, open-label, randomised controlled trial.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-19)Background - Current evidence supports the use of intravenous thrombolysis with alteplase in patients with wake-up stroke selected with MRI or perfusion imaging and is recommended in clinical guidelines. However, access to advanced imaging techniques is often scarce. We aimed to determine whether thrombolytic treatment with intravenous tenecteplase given within 4·5 h of awakening improves functional ... -
Implementing Electronic Health Records – Cases, Concepts, Questions
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023)Learning is inherently social. This raises several questions that relate to how contexts and spaces can mediate co-creative learning. In this workshop proposal, we refer to the interrelated aspects of space, learning, and embodiment and how these aspects mediate the human-robot interaction. Our assumption is that robots are interpreted variously and used in different ways. We are interested in the ... -
Echoes from Intrinsic Connectivity Networks in the Subcortex
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-27)Decades of research have greatly improved our understanding of intrinsic human brain organization in terms of functional networks and the transmodal hubs within the cortex at which they converge. However, substrates of multinetwork integration in the human subcortex are relatively uncharted. Here, we leveraged recent advances in subcortical atlasing and ultra-high field (7 T) imaging optimized for ... -
Sexual Incentive Motivation
(Chapter; Bokkapittel, 2023-05-17)Motivation can be described as the processes that activate, direct, and determine the persistence of goal-directed behavior. A certain level of sexual motivation is required to activate approach behavior which could potentially lead to copulation and reproduction. Here, we discuss the use of the sexual incentive motivation test to assess the magnitude of sexual motivation in rodents in response to ... -
Samtykke fra mindreårige. Implikasjoner rundt barns samtykke til informasjonsdeling i tverretatlig samarbeid.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-19)For å sikre helhetlig oppfølging av utsatte barn og unge er samarbeid på tvers av tjenester et uttalt mål i offentlig sektor, og det følger også av lov. En samordnet innsats fordrer informasjonsdeling mellom tjenester, hvilket medfører utfordringer knyttet til blant annet taushetsplikt, samtykke og personvern. I enkeltsaker kan det være krevende å avgjøre hvorvidt en mindreårig er samtykkekompetent. ... -
No effect of omega-3 polyunsaturated fatty acid supplementation on inflammatory markers in familial hypercholesterolemia: a randomized crossover trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-31)Individuals with familial hypercholesterolemia (FH) have increased cardiovascular risk despite lipid-lowering therapy, and additional therapy is warranted. Omega-3 polyunsaturated fatty acid (n-3 PUFA) supplements have demonstrated an effect on cardiovascular endpoints in some clinical trials. Platelet-modifying and anti-inflammatory properties are among the proposed beneficial effects of n-3 PUFA. ...
