Now showing items 381-400 of 11124

    • A randomized trial on three different minimally invasive decompression techniques for lumbar spinal stenosis. Five years follow-up from the NORDSTEN-SST 

      Hermansen, Erland; Indrekvam, Kari; Franssen, Eric; Myklebust, Tor Åge; Austevoll, Ivar Magne; Hellum, Christian; Storheim, Kjersti; Bånerud, Ingrid Fjeldheim; Ebbs, Eira Kathleen; Aaen, Jørn Ståle; BANITALEBI, HASAN; Brox, Jens Ivar; Weber, Clemens; Solberg, Tore; Hjulstad, Arild; Brisby, Helena (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-24)
      Purpose The short-term clinical outcome for midline-preserving posterior decompression techniques was comparable. The aim of this study was to evaluate long-term clinical results after three different midline-preserving posterior decompression techniques.<p> <p>Material In the NORDSTEN spinal stenosis trial (NORDSTEN-SST) 437 patients were randomized to three different midline-retaining ...
    • Prisforedrag - Norsk Cardiologisk Selskaps forskningspris 2023 

      Løchen, Maja-Lisa (Journal article; Tidsskriftartikkel; Peer reviewed, 2024)
      Det var en stor ære for meg å motta forskningsprisen. Jeg er takknemlig, ydmyk og stolt overfor Norsk cardiologisk selskap (NCS) og juryen. Få fra miljøet i Tromsø har mottatt prisen, og innenfor fagområdet preventiv kardiologi er det heller ikke mange prismottakere. Jeg ble veldig glad. Det var en stor begivenhet for meg å bli hyllet av mine kolleger, både fra min egen hjertemedisinske avdeling og ...
    • Sykepleiers erfaring med kommunal akutt døgnenhet i rurale områder 

      Lykkedrang, Hanne; Mehus, Grete (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-01)
      Bakgrunn: Samhandlingsreformen har ført til at flere pasienter mottar behandling i kommunal akutt døgnenhet (KAD) som et alternativ til sykehusinnleggelse. Innføring av KAD i sykehjem i distriktskommuner har gitt sykepleiere i primærhelsetjenesten nye oppgaver og ansvarsområder. Studien er gjennomført i Troms og Finnmark fylke. I distriktskommunene er det store geografiske avstander innad og til ...
    • Sámi Healthcare Staff Experiences of Encounters with Sámi Patients and Their Expectations for Non-Sámi Healthcare Staff 

      Ness, Tove Synnøve Mentsen; Mehus, Grete (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-01)
      Objective: The aim of this study was to explore Sámi healthcare staff experiences in encounters with Sámi patients and their expectations for non-Sámi healthcare staff. Methods: Focus groups and individual interviews with 14 participants were conducted, and the participants’ experiences were subjected to a thematic analysis approach. <p> <p>Results: The findings show that the Sámi healthcare staff ...
    • Impact of the diagnostic label for a low-risk prostate lesion: protocol for two online factorial randomised experiments 

      Bullen, James; Nickel, Brooke; McCaffery, Kirsten; Wilt, Timothy J.; Smith, Jenna; Boroumand, Farzaneh; Parker, Lisa; Millar, Jeremy; Brodersen, John; Dahm, Philipp; Delahunt, Brett; Varma, Murali; Glasziou, Paul; Warden, Andrew; Diller, Lawrence; Billington, Larry; van Rensburg, Christo; Bell, Katy (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-08-09)
      Introduction - Many types of prostate cancer present minimal risk to a man’s lifespan or well-being, but existing terminology makes it difficult for men to distinguish these from high-risk prostate cancers. This study aims to explore whether using an alternative label for low-risk prostate cancer influences management choice and anxiety levels among Australian men and their partners.<p> <p>Methods ...
    • Trends in the quality of maternal and neonatal care in Sweden and Norway as compared to 12 WHO European countries: A cross-sectional survey investigating maternal perspectives during the COVID-19 pandemic 

      Zaigham, Mehreen; Linden, Karolina; Elden, Helen; Delle Vedove, Stefano; Mariani, Ilaria; Kongslien, Sigrun; Drandić, Daniela; Pumpure, Elizabete; Drglin, Zalka; Costa, Raquel; Sarantaki, Antigoni; de Labrusse, Claire; Miani, Céline; Oțelea, Marina Ruxandra; Liepinaitienė, Alina; Baranowska, Barbara; Rozée, Virginie; Valente, Emanuelle Pessa; Vik, Eline Skirnisdottir; Kurbanović, Magdalena; Jakovicka, Dārta; Bohinec, Anja; Dias, Heloísa; Metallinou, Dimitra; Mueller, Antonia N.; Batram-Zantvoort, Stephanie; Handra, Claudia Mariana; Mizgaitienė, Marija; Tataj-Puzyna, Urszula; Bomben, Arianna; Nedberg, Ingvild Hersoug; Voitehoviča, Elīna; Pinto, Tiago Miguel; Lykeridou, Aikaterini; Grylka-Baeschlin, Susanne; Jazdauskienė, Simona; Szlendak, Beata; Sacks, Emma; Lazzerini, Marzia (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-21)
      Introduction: Maternal-neonatal healthcare services were severely disrupted during the COVID-19 pandemic in even high-income countries within the World Health Organization (WHO) European Region. The objective of this study was to compare trends in the quality of maternal and neonatal care (QMNC) in Sweden and Norway to 12 other countries from the WHO European Region during the COVID-19 pandemic, and ...
    • FKRP-related limb-girdle muscular dystrophy R9 in Norway – Studies of epidemiology, natural history, and relationships with health-related quality of life and sleep 

      Jensen, Synnøve (Doctoral thesis; Doktorgradsavhandling, 2024-12-06)
      <p><i>Background/aims:</i> Limb-girdle muscular dystrophy R9 (LGMDR9) is a rare autosomal recessive muscle disease caused by mutations in the fukutin-related protein gene, FKRP. The prevalence is higher in northern European populations, where it is closely associated with the FKRP c.826CA allele. This work aims to study the epidemiology of LGMDR9 in Norway, natural history, and relationships with ...
    • The SRC-family serves as a therapeutic target in triple negative breast cancer with acquired resistance to chemotherapy 

      Egeland, Eivind Valen; Vasiliauskaite, Kotryna; Skourti, Eleni; Øy, Geir Frode; Pettersen, Solveig; Pandya, Abhilash D.; Dahle, Maria A.; Haugen, Mads; Kristian, Alexandr; Nakken, Sigve; Engebråten, Olav; Mælandsmo, Gunhild Mari; Prasmickaite, Lina (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-10)
      BACKGROUND: Resistance to chemotherapy, combined with heterogeneity among resistant tumors, represents a significant challenge in the clinical management of triple negative breast cancer (TNBC). By dissecting molecular pathways associated with treatment resistance, we sought to define patient sub-groups and actionable targets for next-line treatment.<p> <p>METHODS: Bulk RNA sequencing and reverse ...
    • Factors Associated With Prescription of Systemic Therapy in Real-world Patients With Metastatic Renal Cell Cancer Managed in a Rural Region 

      Nieder, Carsten; Stanisavljevic, Luka; Haukland, Ellinor Christin (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-03)
      Background/Aim: Numerous new treatment options have been approved for metastatic renal cell carcinoma (mRCC) in the last decade. Nevertheless, not all patients receive systemic therapy. Certain patients present with very advanced disease, poor Eastern Cooperative Oncology Group performance status (ECOG PS), or severe comorbidity, i.e. factors that lead oncologists to prefer best supportive ...
    • How Do Pharmacists Distribute Their Work Time during a Clinical Intervention Trial?—A Time and Motion Study 

      Holis, Renata Vesela; Elenjord, Renate; Lehnbom, Elin Christina; Andersen, Sigrid; Fagerli, Marie; Johnsgård, Tine; Zahl-Holmstad, Birgitte; Svendsen, Kristian; Waaseth, Marit; Skjold, frode; Garcia, Beate Hennie (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-09)
      Emergency departments (EDs) handle urgent medical needs for a diverse population. Medication errors and adverse drug events pose safety risks in the ED. Clinical pharmacists, experts in medication use, play a crucial role in identifying and optimizing medication therapy. The aim of this study was to investigate how clinical pharmacists introduced into the ED interdisciplinary teams distribute ...
    • Longitudinal lung function trajectories in response to azithromycin therapy for chronic lung disease in children with HIV infection: a secondary analysis of the BREATHE trial 

      Madanhire, Tafadzwa; McHugh, Grace; Simms, Victoria; Ngwira, Lucky; Gonzalez-Martinez, Carmen; Semphere, Robina; Moyo, Brewster; Calderwood, Claire; Nicol, Mark; Bandason, Tsitsi; Odland, Jon Øyvind; Rehman, Andrea M.; Ferrand, Rashida A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-12)
      Background - Chronic lung disease (CLD) is common among children with HIV (CWH) including in those taking antiretroviral therapy (ART). Azithromycin has both antimicrobial and anti-inflammatory effects and has been effective in improving lung function in a variety of lung diseases. We investigated lung function trajectories among CWH with CLD on ART enrolled in a randomized controlled trial of ...
    • Sámi community perspectives on the COVID-19 pandemic: a mixed methods case study in Arctic Sweden 

      Stoor, Jon Petter Anders; Sedholm, Oscar; San Sebastián, Miguel; Nilsson, Lena Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-25)
      The COVID-19 pandemic posed a grave threat not only to Indigenous people’s health and well-being, but also to Indigenous communities and societies. This applies also to the Indigenous peoples of the Arctic, where unintentional effects of public health actions to mitigate the spread of virus may have long-lasting effects on vulnerable communities. This study aim was to identify and describe Sámi ...
    • Functionally impaired children and their caregivers: A study in a clinical neuropaediatric setting on validity and usefulness of screening instruments completed by caregivers, and caregivers' satisfaction with neuropaediatric assessment 

      Kjærandsen, Katarina Maria Smejda (Doctoral thesis; Doktorgradsavhandling, 2024-12-06)
      This dissertation is based on a naturalistic multicentre study in the context of an interdisciplinary assessment in neuropediatric clinics. The main objective was to expand knowledge about this assessment, focusing primarily on the role of screening instruments completed by caregivers and their satisfaction with the assessment. The validity and usefulness of screening tools for parental mental health ...
    • Podoplanin expressing macrophages and their involvement in tertiary lymphoid structures in mouse models of Sjögren’s disease 

      Hovd, Aud-Malin Karlsson; Nayar, Saba; Smith, Charlotte G; Kanapathippilai, Premasany; Iannizzotto, Valentina; Barone, Francesca; Fenton, Kristin Andreassen; Pedersen, Hege Lynum (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-09-17)
      Tertiary lymphoid structures (TLSs) are formed in tissues targeted by chronic inflammation processes, such as infection and autoimmunity. In Sjögren’s disease, the organization of immune cells into TLS is an important part of disease progression. Here, we investigated the dynamics of tissue resident macrophages in the induction and expansion of salivary gland TLS. We induced Sjögren’s disease by ...
    • Exploring views among Norwegian Sámi regarding gambling and gambling treatment 

      Devold, Marte Reikvam; Spein, Anna Rita; Barua, Pia; Indset, Marie Pedersen; Syvertsen, Andre; Pallesen, Ståle (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-09-19)
      Aim: To explore gambling in the indigenous Sámi culture by studying thoughts, ideas and attitudes towards gambling among Sámi and people living in majority Sámi areas with knowledge of the culture. <p> <p>Methods: The topic was investigated in an inductive thematic analysis of semi-structured interviews with 14 people (n = 13 self-reported Sámi ethnicity). <p> <p>Results: The majority of the ...
    • Nutritional quality of diet characterized by the Nutri-Score profiling system and cardiovascular disease risk: a prospective study in 7 European countries 

      Deschasaux-Tanguy, Mélanie; Huybrechts, Inge; Julia, Chantal; Hercberg, Serge; Sarda, Barthélémy; Fialon, Morgane; Arnault, Nathalie; Srour, Bernard; Kesse-Guyot, Emmanuelle; Fezeu, Léopold K.; Biessy, Carine; Casagrande, Corinne; Hemon, Bertrand; Weiderpass Vainio, Elisabete; Pinho, Maria G.M.; Murphy, Neil; Freisling, Heinz; Ferrari, Pietro; Tjønneland, Anne; Nielsen Petersen, Kristina Elin; Katzke, Verena; Kaaks, Rudolf; Schulze, Matthias B.; Masala, Giovanna; Pala, Valeria; Panico, Salvatore; Ricceri, Fulvio; Verschuren, W.M.Monique; Boer, Jolanda M.A.; van der Schouw, Yvonne T.; Skeie, Guri; Agudo, Antonio; Molina-Montes, Esther; Huerta, José María; Moreno-Iribas, Conchi; Ericson, Ulrika; Sonestedt, Emily; Strid, Anna; Oskarsson, Viktor; Tong, Tammy Y.N.; Heath, Alicia K.; Aglago, Elom K.; Danesh, John; Riboli, Elio; Gunter, Marc J.; Touvier, Mathilde (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11)
      Background - Nutri-Score is a scientifically validated 5-color front-of-pack nutrition label reflecting the nutrient profile of foods. It has been implemented in several European countries on a voluntary basis, pending the revision of the European labeling regulation. Hence, scientific evidence is needed regarding the ability of the nutrient profile underlying the Nutri-Score (uNS-NPS, 2023-updated ...
    • Theoretical Underpinnings of the Political Priorities of Municipal Healthcare Services in Norway. How a Rawlsian Heuristic Can Aid Political Decision-Making in Municipal Healthcare Services 

      Rød, Daniel Andre Voll; Stensen, Vegard; Krane, Martin Sollund (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-11)
      This paper aims to discuss the current criteria for municipal priorities in municipal healthcare services in Norway in light of major theories from political philosophy on social justice, such as John Rawlsʼs theory of justice and utilitarianism. Our first goal is to show that perspectives from political philosophy could prove useful for increasing our understanding of the current priority-setting ...
    • Tildelingsfunksjonens rolle i prioritering av kommunale tjenester 

      Angelsen, Villy; Hartviksen, Trude Anita; Solbakken, Rita; Holm, Solrun Gjertine (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-11)
      Bakgrunn: Den demografiske utviklingen, med økt antall og andel eldre, krever strengere prioritering av ressurser innenfor kommunale helse- og omsorgstjenester. Tildelingsfunksjonen har en viktig rolle i prioriteringen av tjenester på faglig nivå. Med utgangspunkt i teori om styringsmodeller i offentlig sektor belyser studien forskningsspørsmålet: Innenfor hvilke organisatoriske rammer skjer ...
    • Virtually isolated: social identity threat predicts social approach motivation via sense of belonging in computer-supported collaborative learning 

      Bick, Nathalie; Froehlich, Laura; Voltmer, Jan-Bennet; Raimann, Jennifer; Reich-Stiebert, Natalia; Seidel, Niels; Burchart, Marc; Martiny, Sarah E.; Nikitin, Jana; Stürmer, Stefan; Martin, Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-09-13)
      Collaboration improves multiple academic and social outcomes. Accordingly, computer-supported collaborative learning (CSCL) can be beneficial in distance education contexts to overcome the issues specific to online learning (e.g., underperformance, low identification with university). Distance universities often attract a substantial number of non-traditional students (e.g., students with disability, ...
    • Is smokeless tobacco a healthier option in patients with AUD? A follow-up study during treatment 

      Lien, Lars; Bolstad, Ingeborg; Bramness, Jørgen Gustav (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-09-20)
      Introduction - Smoking is negatively related to mental health, but there is a paucity of research on the relationship between the use of smokeless tobacco, such as snus, and mental health outcomes, especially in people with alcohol use disorders (AUD). The aim of the present study was to examine the development of mental distress and quality of life (QoL) among AUD patients in treatment who did or ...