• Fluorescence fluctuation-based super-resolution microscopy using multimodal waveguided illumination 

      Opstad, Ida Sundvor; Hansen, Daniel Henry; Acuña Maldonado, Sebastian Andres; Ströhl, Florian; Priyadarshi, Anish; Tinguely, Jean-Claude; Dullo, Firehun Tsige; Dalmo, Roy Ambli; Seternes, Tore; Ahluwalia, Balpreet Singh; Agarwal, Krishna (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-19)
      Photonic chip-based total internal reflection fluorescence microscopy (c-TIRFM) is an emerging technology enabling a large TIRF excitation area decoupled from the detection objective. Additionally, due to the inherent multimodal nature of wide waveguides, it is a convenient platform for introducing temporal fluctuations in the illumination pattern. The fluorescence fluctuation-based nanoscopy technique ...
    • Two-dimensional TIRF-SIM–traction force microscopy (2D TIRF-SIM-TFM) 

      Barbieri, Liliana; Colin-York, Huw; Korobchevskaya, Kseniya; Li, Di; Wolfson, Deanna; Karedla, Narain; Schneider, Falk; Ahluwalia, Balpreet Singh; Seternes, Tore; Dalmo, Roy Ambli; Dustin, Michael L.; Li, Dong; Fritzsche, Marco (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-12)
      Quantifying small, rapidly evolving forces generated by cells is a major challenge for the understanding of biomechanics and mechanobiology in health and disease. Traction force microscopy remains one of the most broadly applied force probing technologies but typically restricts itself to slow events over seconds and micron-scale displacements. Here, we improve >2-fold spatially and >10-fold temporally ...